In contrast, non-stimulant medications (primarily based on atomoxetine) showed a trend of risk reduction, though not reaching statistical significance [ 14 , 16 ].
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In another study [ 28 ], HD-tDCS had no significant effect on Brief Assessment of Cognition in Schizophrenia (BACS) scores, while HD-the-ta-tACS showed a trend-level improvement ( p unadj = 0.09), though not significant after false discovery rate (FDR) correction ( p -FDR=0.23).
First, hepatocytes isolated from overnight-fasted mice exhibited increased glucose output only in response to glucagon and dibutyryl-cAMP (db-cAMP), a membrane-permeable analog of cAMP, while HYAL1 showed a trend towards suppressing gluconeogenesis in both conditions.
Melatonin treatment, however, showed a trend toward reducing ROS levels in the 16-hour radiation group, although this decrease was not statistically significant.
There was no significant difference between the cyclophosphamide, doxorubicin, vincristine, prednisone and etoposide regimen and the cyclophosphamide, vincristine, doxorubicin and prednisone regimen, whereas combinations with chidamide showed a trend toward an improved PFS.
The age group showed a trend toward association, although it was not statistically significant ( p = 0.121).
While femoral cementation showed a trend towards greater IKS improvement (+87), and tibial cementation was associated with slightly better gain in flexion (+12°), both not clinically relevant, neither difference reached statistical significance after adjustment when compared to fully cementless fixation.
Although overnight exposure to Arabica alone showed a trend toward increased synaptic density, this change was not statistically significant compared with vehicle control (Fig. 3 G).
In the pooled analysis, DOACs showed a trend toward fewer DVTs, but this did not reach statistical significance.
The most common causes of perioperative death in liver failure are severe jaundice and insufficient residual liver volume, which greatly increase the risk of death [ 14 , 17 , 18 ].Based on our findings regarding overall complication rates, combined vascular resection, particularly HAR (OR = 1.27), showed a trend towards increased risk, though this was not statistically significant.
Operative time showed a trend favoring TELD but did not reach significance.
Pre‐biopsy MRI showed a trend toward reduced upgrading in both the full cohort and the GG1 subgroup, though not statistically significant.
The Kaplan–Meier analysis showed a trend toward improved OS among patients with high STING-expressing tumors, with a median OS of 74.7 months versus 25.4 months in the high- and low-expression groups, respectively, although this difference was not statistically significant (log-rank P = 0.06; Supplementary Figure S6 , available at https://doi.org/10.1016/j.esmoop.2026.106908 ).
Dry matter weight With a reduction in N application rate, the DMW at different growth stages and phases showed a trend of N100>N80>N60 ( Tables 3 , 4 ).
In contrast, response to formylmethionyl-leucyl-phenylalanine was higher in subjects with ISM than in subjects with HαT and showed a trend of being higher than in HCs.
However, supplementation with 800 ppm quercetin showed a trend toward alleviating the reduction in FI and BWG caused by high stocking density.
Data for bezafibrate over 2 years showed a trend in pruritus reduction versus placebo that was not statistically significant ( 6 ).
Interestingly, the Pi * MZ genotype was the only SNV statistically significantly associated with HCC development during follow‐up in our study, as PNPLA3 only showed a trend in our longitudinal analysis.
Short-telomere patients showed a trend toward increased proportion of pro-fibrotic SPP1 hi MLMs, with enhanced expression of fibrotic genes compared to patients with normal telomere length.
Although data on patients with non–ST-segment elevation myocardial infarction (NSTEMI) were more limited, the available evidence showed a trend consistent with the overall results of the meta-analysis.
Mobile tumors showed a trend toward a higher risk of thromboembolism, although this increase was not statistically significant.
Multivariate analysis identified procedural success as an independent protective factor for mortality (HR 0.41), while V-sTR and high-dose diuretic use showed a trend toward worse outcomes. 27 The EuroTR registry, including 641 patients treated with T-TEER, confirmed these findings.
In contrast, they showed a trend toward reduced leftward asymmetry (i.e., a rightward shift) in the angular gyrus.
Antioxidant NRF2 expression, oxidative stress, and inflammation levels In patients with severe heat stroke, MDA levels were significantly elevated and showed a trend of gradually increasing with the progression of the disease ( Figure 6A ).
Although the glucocorticoid-treated group (OR = 3.55, 95% CI: 0.04–333.09, P = 0.584) showed a trend toward higher risk, this did not reach statistical significance.