Barely Significant
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“showed a trend”

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In contrast, multiple cohorts of male and female Acsl5 KO mice fed chow diet from weaning showed a trend toward lower body fat, with BW and LBM that were not different from WT ( Table 1B ); when normalized body fat data were pooled from all male and female chow-fed cohorts, KO mice showed a modest but significant 10% decrease (WT: 100% ± 47% [n = 144] vs KO: 90% ± 40% [n = 138], P < .05), confirming HTPS data.
The univariate analysis comparing ruptured and unruptured AVMs, showed that the two groups were similar for demographics, AVM side and size; moreover, the difference in terms of nidus topography with higher and lower motor risk was not statistically significant between the two groups and, as a consequence, pre- and post-operative mRS was significantly higher in the ruptured AVM due to the persistence of motor deficit after bleeding that in fact showed a trend (Table 2 ).
CTEPH also showed a trend towards decreased weight gain on follow-up ( Table 2 ). 3.2 Severe CTEPH is accompanied by RV dysfunction On echocardiography, CTEPH presented lower TAPSE, increased RVWT as well as both short PA acceleration times and lengthened ejection times with late systolic notching in PA flow on pulsed-wave Doppler.