IHC analysis showed a trend toward reduced PLG expression in ccRCC tissues compared with adjacent normal tissues (Fig. 9 A).
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Elevated IL11 expression showed a trend toward reduced overall survival and was significantly associated with poorer disease-free survival.
Additionally, the WFH z-score showed a trend towards improvement in the ONS group, but the difference was not statistically significant [mean difference 0.13 (− 0.02 to 0.27)] (Table 4 ).
Although no statistically significant associations were observed, older age and tumour size (≥ 3 cm) showed a trend toward an increased risk of upstaging (Supplemental Table 4).
AI patients showed a trend for significantly increased odds of having advanced-stage RCC (OR 3.70, 95% CI 0.99–13.81).
With increasing BF% quartiles, participants showed a trend of progressively older age (Q1: 33.98 ± 6.82 years; Q4: 50.08 ± 12.73 years), while the proportion of males decreased significantly (Q1: 98.27%; Q4: 12.67%).
Adiponectin, an anti-inflammatory adipokine, showed a trend toward higher expression (Fig. 3 A), and perilipin-1 ( Plin1 ) as a marker for adipocyte identity showed substantially higher levels in PVAT-derived cells on TPU than in those on TCPs.
Despite nearly triple pollen exposure in 2025 compared with 2024 (2850.6 vs 960.3 grains/cm 2 ) ( Fig 1 ), nasal and ocular symptom scores in patients with RA showed a trend toward improvement compared with those in 2024, with reductions of approximately 30% to 60%.
3.2 Multi-contamination in different functional areas In water, ARG abundance showed a trend of industrial area > agricultural area > commercial/residential area, though absolute differences were modest ( Fig. 3 A, Table S3 ).
Caucasian ethnicity showed a trend toward a lower likelihood of CAD compared with non-Caucasian ethnicity; however, this association did not reach statistical significance after multivariable adjustment (OR 0.51, 95% CI 0.26–1.03, p = 0.067).
Finally, although melatonin implants showed a trend toward improved antioxidant status in these heifers, higher concentrations may yield pronounced clinical effects, as suggested by dose–response patterns reported in some antioxidant supplementation trials.
Among MT, FL, and PA, only FL showed a trend-level positive association with interhemispheric M1 connectivity in SP, on top of the local M1 activation.
Use of ICG showed a trend reducing the risk of UIAS without reaching statistical significance, whereas individual analysis did not show a significant reduction.
Morphometric analysis of trichrome-stained lung sections showed that mean linear intercept (MLI) was unchanged at day 14 (Supplementary Figure S4A, B), consistent with early-stage fibrosis, while alveolar septal thickness, significantly elevated in silica-exposed controls showed a trend toward reduction in alveolar epithelial Nlrp3 -deficient mice (Supplementary Figure S4C).
WB results showed a trend slightly different from that of PCR data, but protein expression levels for OCN, OPN, SP7, and others peaked at 6 h of stretching ( Fig. 3 E, Fig.
TJ-14 showed a trend in reducing the risk of afatinib-induced diarrhea, and minocycline reduced the risk of afatinib-induced skin rash [ 49 ].
On 1 Jul, the net photosynthetic rate, transpiration rate and stomatal conductance of W2F2 treatment were the largest, and the net photosynthetic rate, transpiration rate and stomatal conductance of each period showed a trend of increasing first and then decreasing, and the intercellular carbon dioxide concentration showed a trend of decreasing first and then increasing.
Physical activity positively correlated with MD adherence and showed a trend toward lower severity.
V940 added to adjuvant pembrolizumab improved distant metastasis-free survival and showed a trend toward prolonged progression-free survival without introducing new safety signals, with adverse events mainly consisting of flu-like symptoms [ 72 ].
In the present study, the thymidine content of the model group rats was abnormal, while the Ai pian group showed a trend of returning to the levels of the sham operation group.
At the whole T-cell level, Rs showed a trend toward higher cytotoxic program activity with broadly comparable exhaustion (Supplementary Fig.
In univariable Cox regression analysis, high B7-H3 expression was significantly associated with inferior OS and showed a trend toward worse EFS ( Table 2 ).
Among highly infiltrated samples, the median proportion of Tex in MSS CRC showed a trend towards being higher, although not statistically significant (Extended Data online supplemental figure 2j).
When cells were seeded at a density of 200 cells/well in ultra-low-attachment 96-well plates, the shNT group formed significantly larger spheroids, and the total number of spheroids formed (diameter >100 μm) was notably higher, whereas the shCTSZ group showed a trend toward forming smaller spheroids.
Duration showed a trend toward poorer outcomes with increasing duration, though this was not statistically significant.