t-IR levels were similar in allergic and control mice; however, allergy was associated with a significant decrease in the levels of p-IR [95% CI 0.01- 0.31; P < 0.05] in the hippocampus (Figure 6 ) but not in the frontal cortex and hypothalamus, although the data showed a trend similar to that in the hippocampus (data not shown).
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Our data also showed a trend for LGE-CMR scar size as a predictor for ICD therapy.
Glutamate concentrations showed a trend similar to the total amino acids; at 144 and 192 hpe, concentrations reached a twofold higher level in non-treated cuttings compared with NPA-treated cuttings (Fig. 8 b).
Compared with the vehicle-treated group,EEP significantly reduced the levels of ET and VEGF,and showed a trend to increase NO and inhibit iNOS.
Subjects 542, 608, 677, and 712 all showed a trend for discordant CD4 downregulation but failed to reach statistical significance (p-value range 0.10–0.17).
Upon EA supplementation, we observed SREBP2 to be statistically significant up-regulated and SCAP to be statistically significant down-regulated, while Insig2 showed a trend towards up-regulation (but was not found to be statistically significant).
Longer sleep duration showed a trend towards correlation with higher LDL while higher PSQI score correlated with higher LDL in model one.
At 6 months, scores showed a trend towards beneficial midterm outcomes for both groups without significant differences between the two groups.
Mice injected with des-His 1 -Glu 9 -GCG at both doses (2 and 4 mg/kg) showed a trend toward the attenuated increase in blood glucose as compared with vehicle-treated animals ( Fig. 9 , A and B ).
Although no significant improvement was detected with 50 or 100 ng/ml of IGF-1 administration after 12 h of exposure to hypoxic conditions (p>0.05 versus hypoxia group; n=5), these doses of IGF-1 showed a trend toward a decrease in the number of apoptotic cells after 12 h of hypoxic damage, as shown in Figure 2B .
Although the pre-HD group showed a trend in the same direction, the difference between pre-HD and symp-HD exhibited only a trend toward significance ( p = .058), and the difference between pre-HD and controls was not significant (see Figure 1 and Table 2 ; see Tables S1 and S2 for a full inventory of longitudinal within- and between-group regression coefficients and their statistical significance).
The beneficial effects of roflumilast on lung function were initially demonstrated in patients with moderate-to-severe COPD and severe COPD.[ 266 , 267 ] Both studies showed a trend towards lesser exacerbations with the use of roflumilast.
Detection of p62 by immunoblotting showed a trend towards decreases p62 levels in the VitC deficient PMNs ( Figure 3 C).
After UCMS, gonadal males showed a trend for less time and percent distance in the center of the OF (Figure 7 B; higher anxiety-like behavior) than gonadal females.
Thirty percent of analyzable tumor samples were found to have a PTEN deletion determined using FISH, and those in particular showed a trend toward longer PFS after treatment.
The expression of OC showed a trend for higher expression in the MSCs receiving exosomes (1.7±0.4), while the expression was significantly decreased when the MSCs were cultured in the full CM (0.5±0.0, Fig 3c ).
In the setting of HIV infection, a study, in mostly treated patients, showed a trend towards lower 25(OH)D levels in persons both in the lower and higher BMI tertiles [18] .
While the progression-free survival was improved, the overall survival (OS) showed a trend toward a detrimental effect with the tivozanib arm with a median OS of 28.8 months versus 29.3 months in the sorafenib arm based on the pre-new drug application (NDA) meeting with the US Food and Drug Administration (FDA) [ 29 ] which later led to the FDA ODAC meeting to disapprove tivozanib as an indication for RCC.
In further analysis, we found that around 35 patients received colistin and/or tigecycline, of them 21 (60%) survived, thought not statistically significant, but showed a trend that the use of these two antibiotics in patients with CRA-VAP leads to a better outcome.
One recent cohort study of invasive breast carcinoma selected to pair with NEBC reported that NEBC showed a more aggressive course than invasive ductal carcinoma and that regional lymph node metastasis showed a trend for predicting poor overall survival [24] .
Presently, 0.1 μ mol/kg YZ-185 did not significantly affect the development of CPP to cocaine, but showed a trend toward enhancement.
Patients deficient/insufficient in vitamin D showed a trend towards higher CRP levels than those sufficient in vitamin D, but this difference was not statistically significant.
Carriers of the DAT 10/10-repeat allele showed a trend towards higher frequency of neurocognitive impairment (32 %) according to the HDS/IHDS and GDS compared to 21 % impairment for carriers of the non-10/10 alleles (Table 2 ).
Microscopic analysis of the ovaries showed a trend to lower numbers of follicles – especially at the antral stage – in Asah1 P361R/P361R mice ( Fig 2B ) .
18 , 28 , 29 , 30 , 50 Results of our study also showed a trend toward the belief that bioidentical estradiol is more effective than other estrogens for menopause-related vasomotor symptoms but associated with a higher risk of breast cancer ( Table 5 ).There was also a small trend favoring progesterone over MPA with regards to beliefs of effectiveness (menopause related vasomotor symptoms and improving quality of life) and safety ( Table 5 ).