DISCUSSION This study showed a trend of increasing prevalence of skin test positivity among school children and students with the increasing age (from primary school children to undergraduate students).
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Regarding the concentrations of albumin, our results showed a trend of gradual increase with age being the highest on days 32 and 46 of fattening, thus helping to maintain the metabolic balance during the period of rapid growth.
Although less than 30% of the AZA patients completed the planned 12 cycles, the study showed a trend toward improvement in RFS in the patients receiving more AZA cycles. 101 Maintenance with CC-486, a novel oral AZA formulation that allows extended dosing and prolonged activity, has also been explored, although with limited data on frequency of prior therapy with HMAs. 98 Thirty patients in CR after alloSCT received CC-486 once daily for 7 or 14 days in a 28-day cycle for up to 12 cycles and among these, 9 had received AZA prior to transplant.
Further correlation analyses showed a trend toward negative correlation between serum pre-existing αAAV9 Abs and tissue AAV vg copy levels in the brain, liver, heart, kidney, and lung ( Figure 4 ), though it did not reach statistical significance (p > 0.05).
Kinetic data indicated that the releasing capacity of the acid showed a trend to increase from 5 to 15 min of cell exposure and then it remained almost stable up to 30 min ( Figure 2A ) indicating granular histamine depauperation in the absence of a fast re-synthesis.
The two rivers showed a trend of “wet-dry-wet-dry”, were the Pearl and Rhine rivers, but the mutation time of the Pearl River relatively lagged behind the Rhine River.
Analyses of group and individual outcomes showed a trend toward improvement in ASD symptoms (i.e., a reduction in repetitive behaviors including stereotyped behaviors and compulsive behaviors, such as lack of flexibility), which are related to self-regulation.
After exclusion of TCF7L2 rs7903146 from the risk score the interaction effect remained significant, indicating that the effect was not only driven by the TCF7L2 SNP that showed a trend for interaction with coffee in the single SNP analysis.
When the authors compared treated patients with historical controls as in our study, they showed a trend towards a treatment benefit on time to reach EDSS 6.0 (relative risk 0.77, CI 0.58 to 1.02), which is comparable with our results considering they had a much smaller treated cohort (n=868 vs 4986) with shorter follow-up time (mean 5.2 and median 5.1 years vs 8.7 and 10 in our study).
Moreover, the delay time and intensity of association showed a trend.
An eight-year prospective study of MRSA in a surgical ICU showed a trend towards increasing prevalence of the resistance gene qacA/B [ 60 ].
The CDVA, PROS, FOSPET and FPR showed a trend toward progressive decline when analyzed across pedigree subgroups with simplex or sporadic cases being the best and X-linked, the worst (Table 3 ); however, apart from PROS, the differences did not reach statistical significance.
Conversely, FH6-8 showed a trend, which did not reach statistical significance, toward a reduction in RBC adhesion ( Figure 3B ).
coli O111:B4 serotype, a known stimulator of nitric oxide synthase (NOS) in human hepatocytes [ 27 ], significantly decreased the expression of miR-181a, whilst treatment with 100 ng/ml showed a trend towards decreased expression of miR-181a and both 10 ng/ml and 100 ng/ml non-significantly decreased miR-21 expression.
Isolated CD8 + T cells obtained from MC38‐MOCK tumors indeed displayed higher reactivity toward two of the neoantigens, while the response to the third antigen showed a trend toward higher recognition (Fig. 4 c ).
Furthermore, since large numbers of tumors are necessary for survival analysis in NMIBC, in our multivariate analysis THOR High /TERTp Mut only showed a trend toward significance as a risk factor for disease progression.
Subgroup analysis showed a trend towards benefit with the left anterior descending (LAD) artery CTO revascularisation cohort where the most functional benefit would be expected.
In middle-aged females, IC (L) showed a trend toward a significant positive effect on the lysozyme-like activity.
Regression analysis showed a trend of positive correlation between C-peptide level and MoCA score in the control group, but no positive findings in the whole cohort or the MCI group.
Experiment 4: Assessing the effect of using dirty water on the accuracy When dirty water was used to count larvae, results showed a trend for reduced accuracy.
Even with the lower intake of fibers than the recommended guidelines, constipation showed a trend towards improvement.
However, the statistical power may be inadequate to highlight some of the differences that were found not to be statistically significant in the study but that showed a trend toward it.
The changes for OPG and sclerostin they observed were not statistically significant but showed a trend in the same direction [ 84 , 85 ].
We found that the small intestine microbiota showed a trend towards greater diversity than the colon microbiome, across a number of diversity score metrics and patient populations.
For the majority of samples in the 1–4 logPAH-DNA range, IFNg, IL-1b, IL-2, IL-10 and IL-17A showed a trend towards a decrease in these immune parameters.