“showed a trend”

Our data showed a trend towards impaired spatial memory of 5xFAD mice, which however was not improved by rTMS treatment (Additional file 1 : Supplementary Fig. 1a).

Observation of response distribution showed a trend to floor effects for items 6 and 7 and a slight trend to a ceiling effect for item 3.

Although danirixin showed a trend for improved respiratory and health status in patients with COPD ( 7 ), the absence of a clear efficacy benefit has been confirmed in a larger clinical trial ( 13 ).

In line with our morphological findings, Phb1-SCKO animals treated with ISRIB showed a trend toward reduced performance in the rotarod test as compared to Phb1-SCKO mice treated with vehicle (p-values Phb1-SCKO + ISRIB vs Phb1-SCKO + Veh: Day 2 = 0.0936, Day 3 = 0.0979, Day 4 = 0.0723) (Fig. 7f ).

Directly after sorting, Th17/Th22 cells showed a trend towards being the strongest producers of IL-17A, IL-22, and GM-CSF, whereas Th17.1 and DP cells produced the highest levels of IFNγ (Fig. 1 B, upper panel).

In the multivariate logistic regression, indwell duration of TICVAP (odds ratio [OR], 1.13; 95% confidence interval [Cl] 1.02–1.37, p = 0.10), body weight change during indwell (OR, 1.00; 95% Cl 0.83–1.18, p = 0.97), and platelet count at TICVAP insertion (OR, 0.98; 95% Cl 0.95–0.99; p = 0.48) showed a trend toward an increased risk of stuck fragment of TICVAPs during removal.

Quantitative measurement of HMGB‐1 by ELISA (Figure 5G ) showed a trend similar to the immunohistochemistry results (sham‐normoxia and hyperoxia, 199±46, 221±36 ng/mg protein; CA‐normoxia and hyperoxia, 471±51 and 716±49 ng/mg protein; Kruskal‒Wallis; P <0.001, pairwise P =1.000, P =0.528, respectively: Figure 5H ).

Interestingly, the step count showed a trend to increase in the treatment group which was not statistically significant.

22 Although not statistically significant, we also showed a trend toward lower satisfaction in more educated and employed patients.

Moreover, CRT might be harmful, in the European REVERSE substudy, the NYHA class I patients showed a trend toward worsened HF clinical composite response [ 33 ].

Patients with MG and anti‐NRIP autoantibody showed a trend to have unstable MG course (requiring titration of MG‐specific medication within 1 year) compared with those without anti‐NRIP autoantibodies, although the difference did not reach statistical significance ( P = 0.077).

32 In the REHAB‐HF pilot study, a 12‐week rehabilitation programme focused on improving strength, balance, mobility, and endurance showed a trend towards improved physical function and decreased hospitalizations in acute HF patients. 33 Recent evidence suggests that exercise training, combined with nutritional support (e.g. protein/amino acid supplementation, preventing vitamin/mineral deficiencies), has shown considerable benefit in chronic HF patients. 6 , 34 Assessment of urinary creatinine at baseline and during such studies would be of great interest to illustrate an improvement of muscle mass during exercise intervention studies.

In our study, compared with KRAS and the whole LUAD group, the TIME in the EGFR mutant patients showed a trend of diminishing activated TILs and increasing numbers of immunosuppressive cells.

Carotid plaque ipsilateral to stroke side in men showed a trend in higher volumes of all plaque subcomponents although only calcified plaque volume was significantly higher (ipsilateral, 63.9 versus contralateral, 34.1 mm 3 , P =0.03).

The concentrations of NO 2 and CO showed a trend of first rising and then decreasing, it is still necessary to further strengthen pollution prevention and control; the concentration of O 3 kept increasing year by year on the whole.

Finally, in a retrospective study that included solid organ transplant patients with type 2 diabetes mellitus (diagnosed pre- or post-transplant) and stage 3–4 of CKD in more than 70% of the patients, dulaglutide compared with liraglutide showed a trend towards improved kidney function over a 24-month follow-up period [ 96 ].

With moderate confidence, HCQ showed a trend towards reducing the need for mechanical ventilation at 30 days by 7%, with low confidence HCQ showed a trend towards speeding hospital discharge by 3%, and with very low confidence HCQ showed a trend towards improving clinical recovery by 26%.

In serial laboratory tests, LFTs did not decline and showed a trend of fluctuation (Figure 2 ).

TDF showed a trend of unfavorable renal safety even in short term treatment, although there was no statistical difference in 4-week changes of renal function among three groups.

ITGA1 expression was unchanged, whereas ITGA2 showed a trend toward an increased gene expression with higher loading.

The results of qRT-PCR showed that the expression levels of NtGLK3 , NtGLK17 , NtGLK19 , NtGLK39 , NtGLK58 , NtGLK72 , and NtGLK85 were decreased, precisely consistent with the increase of the senescence degrees, while the expressions of NtGLK36 , NtGLK69 , and NtGLK78 showed a trend of rising first and then decreasing ( Figure 9 ).

The results showed a trend of decreasing VAS scores after TKA in both groups ( Figure 1 ).

Conclusions We found no significant difference in successful discontinuation of PPI medication at 12 months using abrupt or taper methods, although participants in the abrupt discontinuation group showed a trend towards earlier relapse and significantly more symptoms occurring up to six months after stopping their PPI.

The gene expression levels of IL-1b, IL-1a, MCP1, and TNFα were significantly higher while CXCL1 and MMP3 showed a trend towards an increase in the aged brainstem ( Figure 2B ).

While the magnitude of the effects of PME-1 overexpression in Tg2576 mice was small and potentially confounded by the emergence of non-cognitive impairments, Tg2576 mice that overexpressed PME-1 showed a trend toward earlier onset and/or increased severity of cognitive and electrophysiological impairments.