In recent years, the incidence rate has increased yearly, and it has showed a trend of being diagnosed in younger people.
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Moreover, LIPA and COL1A2 expression showed a trend towards increasing in parallel with the degree of disease activity, with some significant intergroup differences when NAFLD cases were stratified according to NAS score (Fig. 5 E).
The male mice displayed high variability in both FMN and FAD concentrations, and only the CerS6 KO brains showed a trend for increasing mean cofactor concentrations with increase in dietary FA, which is opposite to the effect observed in the liver.
The study showed a trend toward higher composite all-cause mortality and amputations in the paclitaxel DCB group compared with PTA but this difference did not reach statistical significance (35.2 vs. 25.2%, P = 0.064).
Nonetheless, posterior ETT showed a trend for a higher risk of failure than anterior ETT (adjusted HR = 1.68, 95% CI 0.81–3.45; Table 3 ).
Our meta-analysis of these studies showed a trend toward lower odds of completing a university degree, secondary education, or vocational training.
11 Following a phase I dose‐escalation safety study, a 60‐subject, multisite phase IIa clinical trial showed that PACT‐produced MSCs were well‐tolerated and showed a trend for improvement in oxygenation index in the treated group. 12 A phase IIb trial jointly supported by the Department of Defense and PACT 3/NHLBI is underway at the time of writing this manuscript.
Despite not significant, the rates of women undergoing IOL showed a trend of increase in the group 2 (25.5% versus 38.2%, P : 0.137).
The therapy group showed a trend toward the lowest number of Ki67-positive cells ( Figure 6 E) and a significantly smaller area of CD31 positivity ( Figure 6 F) compared with the control groups.
Heterosexual women showed a trend of larger pupil sizes during the viewing of other-sex (i.e., male) stimuli, but the magnitude of this effect was small and not significant.
PAR1 inhibition by SCH79797 showed wider effects in CD8 T cell function including inhibition of IFNγ secretion and showed a trend in TNFα secretion although it did not reach statistical significance ( Figure S2 F).
Compared to untreated patients, all patients treated with BTA showed a trend towards suppression of bone formation, as measured by tetracycline labelling.
Cerebral infarction showed a trend to higher levels than the pre-pandemic period in the final months of the study period (Fig. 6 , Supplementary Fig. 1 ).
Adult patients who were subsequently prescribed rhPTH(1-84) showed a trend for higher numbers of doctors’ office visits and ED visits in the 12 months before baseline versus those who received conventional therapy (Table 7 ).
In the first dataset of BLAZE-1, bamlanivimab showed a trend towards decreased viral load vs. placebo with a significant difference for the 2800-mg dose [ 30 ].
In contrast, remdesivir use showed a trend to lower mortality risk (aHR, 0.48; 95% CI, 0.23–1.02) ( Figure 1 ).
Regarding survival, even if treatments and follow-up are still ongoing in 17 patients, our study showed a trend in PFS and OS comparable to those of previous cemiplimab trials with long duration of response.
The prognostic significance of BRCA1 expression showed a trend in multivariate analysis (HR: 0.21, 95% CI: 0.04 – 1.11) ( Table 2 ).
Cav-1 KO mice showed a trend toward increased superficial capillary plexus vessel density and branching density in all regions compared to WT, however, only branching density in the mid-region showed a statistically significant difference.
Furthermore, our data showed a trend toward lower objective tumor responses and disease control rates among patients who received lower pre-emptive nal-IRI dosing.
But the EE group showed a trend of recovery in all indexes compared to the M group.
Although the above studies showed a trend towards clinical/biochemical improvement, they did not always achieve their primary end-points.
Sichuan and Guizhou showed a trend of hierarchical decline, with Sichuan falling from medium to a low level, while Guizhou fell to a lower level.
The CFA model showed a trend of increased levels of the major sensory neuropeptide CGRP and Iba1 expression, both of which are indicative of neuronal sensitization and inflammation, which have been associated with pain.
At 10 mpf, pdx1 mutant samples showed a trend towards decreased proliferation in the ONL as compared to controls ( n = 4), which did not reach statistical significance ( Figure 4 f and Figure S2b ).