Cerebral infarction showed a trend to higher levels than the pre-pandemic period in the final months of the study period (Fig. 6 , Supplementary Fig. 1 ).
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Adult patients who were subsequently prescribed rhPTH(1-84) showed a trend for higher numbers of doctors’ office visits and ED visits in the 12 months before baseline versus those who received conventional therapy (Table 7 ).
In the first dataset of BLAZE-1, bamlanivimab showed a trend towards decreased viral load vs. placebo with a significant difference for the 2800-mg dose [ 30 ].
In contrast, remdesivir use showed a trend to lower mortality risk (aHR, 0.48; 95% CI, 0.23–1.02) ( Figure 1 ).
Regarding survival, even if treatments and follow-up are still ongoing in 17 patients, our study showed a trend in PFS and OS comparable to those of previous cemiplimab trials with long duration of response.
The prognostic significance of BRCA1 expression showed a trend in multivariate analysis (HR: 0.21, 95% CI: 0.04 – 1.11) ( Table 2 ).
Cav-1 KO mice showed a trend toward increased superficial capillary plexus vessel density and branching density in all regions compared to WT, however, only branching density in the mid-region showed a statistically significant difference.
Furthermore, our data showed a trend toward lower objective tumor responses and disease control rates among patients who received lower pre-emptive nal-IRI dosing.
But the EE group showed a trend of recovery in all indexes compared to the M group.
Although the above studies showed a trend towards clinical/biochemical improvement, they did not always achieve their primary end-points.
Sichuan and Guizhou showed a trend of hierarchical decline, with Sichuan falling from medium to a low level, while Guizhou fell to a lower level.
The CFA model showed a trend of increased levels of the major sensory neuropeptide CGRP and Iba1 expression, both of which are indicative of neuronal sensitization and inflammation, which have been associated with pain.
At 10 mpf, pdx1 mutant samples showed a trend towards decreased proliferation in the ONL as compared to controls ( n = 4), which did not reach statistical significance ( Figure 4 f and Figure S2b ).
However, for the speleotherapy combined with the exercise group (compared to the exercise alone group), relative treatment effects indicated a more substantial decrease of white blood cell and nasal eosinophilic cell count, suggesting a sustainable improvement effect of the mucociliary clearance time and post hoc test showed a trend in the interaction effect at day 60 for allergic symptoms, revealing a faster return to baseline within the speleotherapy group.
Quantification of the in vivo bioluminescent signal (in the thoracic and lower gut regions) using Living Image ® (PerkinElmer) showed a trend towards increasing in mice administered SAA compared to the respective control, whereas the corresponding quantification of MMP activity in isolated kidneys showed a significant difference. 6.2.
A recent phase 2 clinical study of rhIGF-1/rhIGFBP-3 treatment showed a trend toward decreased occurrence of severe IVH as compared to standard neonatal care [ 16 ].
In contrast, the residential distribution showed a trend of suburbanization and was scattered [ 16 , 53 , 54 ].
Additionally, these oils showed a trend of the increased value of selective ratio over time.
Additionally, the expression of the cholesterol 7α-hydroxylase ( Cyp7a1 ) gene in the liver showed a trend towards an increase in ALS-treated mice, whereas upregulation of the liver Fxr gene was observed ( Figure 6 K,L).
Only the history of cerebrovascular disease and hypertension showed a trend associated with CAPA.
The evolution of CFAI also showed a trend of increasing first and then decreasing, but the turning year was advanced to 2014, and the average annual growth rate of the two stages changed from 2.26% to −2.15% ( Figure 1 ).
Alpha and Beta Diversities In general, two diversity indices (OTU richness and Shannon index) showed a trend to increase following the elevation gradient from the sea, with some exceptions ( Figure 3 ).
VEGF-D showed a trend towards higher levels being secreted from SAT compared to VAT, though this did not reach statistical significance. 2.3.
The timing of the DA episodes also showed a trend in the south–north direction.
The body weight of the mice in the MMC NP and MMC RGD-NP groups showed a trend of slow decrease, while the weight loss in the MMC solution group was more obvious.