“showed a trend”

In addition, a statistical analysis on the docking scores of all ligands were also conducted, and found that the number of docking ligands showed a trend of more in the middle (about −7.5) and less on both sides with the distribution of docking scores ( Figure 4 ), and the distribution trend of docking scores between the two molecules was highly consistent, which indicates that the two molecular docking results are related, and further correlation can be made.

Homozygous Wars2 V117L/V117L mice fail to gain fat mass due to growth and high-fat diet In data from a small cohort of 6-month old Wars2 V117L/V117L males we previously showed a trend towards increased ratio of gWAT:iWAT mass ( Agnew et al., 2018 ).

In that same study, however, the authors showed a trend toward reduced DNMT3A expression in the T2DM islets compared with the non-T2DM islets ( 64 ).

Despite no significant difference in RFS or OS detected between patients with pathologically or model-predicted confirmed GPC-3 expression, Kaplan–Meier survival curves still showed a trend wise longer survival in patients with GPC-3-negative HCC.

Sodium silicate treatment promoted the expression levels of StPOD, StNOX , and the production of ROS During wound healing, the expression of StPOD and StNOX showed a trend of first ascending and then descending ( Figures 5A,B ).

Furthermore, as the groove width increased, the wear scar width showed a trend of first decreasing and then increasing.

Patients with α-syn seeding activity also showed a trend toward a higher prevalence of resting tremor (25.0% vs. 16.2%) (Additional file 1 : Table S4).

The magnitudes of ROC showed a trend of first increasing and then decreasing from the proximal to the distal end of the femoral canal.

Mitochondrial ROS with addition of H 2 O 2 showed a trend towards increased intensity on soft substrates for U251-MG, whereas GL15 showed increased expression on stiff without significant differences ( Supplementary Figure 4 ).

A strong correlation (r ≥ 0.7) was observed for Txnip (r = 0.77), Angptl4 (r = 0.82), Anp (r = 0.99), Pdk4 (r = 0.99), Prdx4 (r = 0.70) and Rgs2 (r = 0.71); Hif1α (r = 0.57) and Glut4 (r = 0.63) showed a trend and a moderate correlation (0.5 < r < 0.7).

Furthermore, the results from national registries in Denmark showed a trend that the long-term use (≥5 years) of low-dose ASA slightly reduces the overall risk of glioma compared to patients receiving the medication for less than 5 years [ 52 ].

The control cell line showed a trend of increasing VLCAD enzyme activity with increasing REN001 concentration that was not statistically significant.

However, with the increase of temperature, the suspension stability showed a trend of first increase, then decrease and then increase, which was related to the change of particle aggregation and fragmentation, and corresponded to the results of particle size. 3.7.

The tumor animals showed a trend of reduced vessel densities and mean vessel lengths at all time points, though these findings were not statistically significant.

While loss of IL-1β restricted to hematopoietic cells showed a trend towards increased levels of IL-1Ra in BM, this trend was not observed in mice with complete loss of IL-1β in all tissues (Supplementary Fig. 7c ), suggesting that the overall activity of IL-1 signaling is reduced when IL-1β is lost in hematopoietic cells only.

However, GBP4 ( P = 0.058) and KLHL41 ( P = 0.061) expression in melanocytes only showed a trend for statistical significance.

And increased CD3 and CD8 showed a trend towards improved OS ( 11 ).

In addition, TNFα alone showed a trend to increase MCF7 cell apoptosis, although the increase of AnnV + PI −/+ apoptotic cells did not reach statistical significance ( Figure 7A ).

Although the combination of mirtazapine with initial AD was still the mainstream regimen, our study showed a trend in prescribing adjunctive antipsychotics, especially quetiapine, indicating that Chinese psychiatrists were adapting their clinical decisions to the up-to-date evidence and guidelines when considering adjunctive agents for poor response.

Our results showed a trend toward increased LBR in the TPO-Ab-negative group, with no statistically significant difference.

2 On the other hand, memory HIV-specific CD8 + T cells in people treated from CHI showed a trend toward higher expression of TOX and significantly higher PD-1 expression than cells in people treated from AHI ( P > 0.0001 and P = 0.05, respectively; Figure 3 c and d).

The results showed a trend of reduced expression levels of three major cytokines (IL-6, TNF-α, and IL-1β) in miR-26a H livers compared to the WT control ( Figure 5 A).

However, Dex-treated control mice showed a trend toward decrease in soluble protein concentration, although the changes were not statistically significant (Supplementary Fig. 12K ).

The density of CD8 + T cells in the left untreated tumor of the treated mice showed a trend but not a statistically significant increase (p=0.0556) likely related to relatively large heterogeneity ( figure 5E, F ).

Methyl-beta cyclodextrin (MβCD), a chemical known to deplete GM1 clusters from the cell membrane, decreased the apparent size of GM1 clusters and showed a trend of decreasing cluster numbers (Supplementary Fig. 2b, c ).