By comparing DSB repair efficiency in the stomachs between the control and mental stress groups, we surprisingly found that mental stress significantly suppressed NHEJ efficiency by 47.4%, while HR efficiency also showed a trend of decline, although not significant, in stomachs ( Figs. 2H , 2I and S5L ).
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Nonetheless, in the current updated analysis, descriptive OS showed a trend in favor of Isa-Kd vs Kd with HR of 0.78 (95% CI: 0.54–1.12) (Supplementary Table S4 ).
Another retrospective study found influenza acquisition in hospital showed a trend to significant association with death when adjusted for age and Charlson score [17] .
ABF3 also showed a trend to bind the F1 fragment ( Fig. 6 ).
2 , 3 , 4 , 5 , 6 , 7 Accumulating evidence from previous studies showed a trend of better survival outcomes in ICI patients who were concomitantly treated with certain medications, such as renin‐angiotensin‐aldosterone system inhibitors (RAASi). 3 , 7 , 8 , 9 , 10 , 11 Experimental studies have shown that the renin‐angiotensin‐aldosterone system (RAAS)
It showed a trend of a longer OS in patients with prior trastuzumab use than those without prior trastuzumab use (median, 8.3 months vs. 4.8 months). 43 The KEYNOTE‐811 trial evaluating the combination of anti‐PD‐1 antibody and HER2‐blockade plus chemotherapy showed remarkable ORR of 74.4%. 44 Meanwhile, it
For prevention of postoperative and postdischarge nausea and vomiting in high-risk patients showed that complete response was not different between the treatment groups for any time intervals, however, the combination group showed a trend toward greater satisfaction, especially in the “nausea domain,” and the combination therapy of palonosetron plus dexamethasone did not reduce the incidence of PONV when compared with palonosetron alone.[ 26 ] Our results corroborate this finding.
RESULTS: Compared to untreated samples, tPA-treated samples showed a trend toward decreased angle and G suggesting potentially clot formation rate and clot strength.
When increasing the CNT concentration, the IFSS performance showed a trend of increasing and then decreasing.
The extraction amount of OCPs showed a trend of first increasing and then decreasing as the temperature increased.
The permeance of the (T-P-T)/PES membranes decreased gradually with the prolongation of the curing time, and the methyl blue rejection showed a trend of increasing first and then decreasing.
It can be seen from Figure 8 b that the heading angle presented a similar sine wave change; it showed a trend of first increasing, then decreasing to zero, then increasing, then decreasing to zero, and then increasing within 24 h.
This exploratory study showed a trend toward decreased mortality in the arm receiving higher oxygenation.
In children with 22q11DS, FW span and BW span showed a trend towards a moderate correlation, but this did not reach statistical significance ( r (36) = 0.29, p = 0.083, 95% CI [− 0.04–0.57]).
However, MSC-Ob showed a trend towards increase in cell death and cellular senescence but decrease in the rate of cell proliferation (Fig.
Interestingly, only addition of low-dose everolimus (mTORC1 inhibitor) to anti-PD-1 led to better bladder or cervical cancer control 124 , 125 , while addition of high-dose everolimus to anti-PD-1 showed a trend towards worse tumour control 124 .
S8 B,F, S9 A,D), this difference may be indicative of variations of gene expression patterns in glioma patients from different countries and regions, almost all the above analyses showed a trend consistent with the results of the TCGA dataset analysis.
At 0.1% O 2 , the NHEJ-related genes were downregulated for H460 and A549 cells with the exception of LIG4 that showed a trend to increase in H460 cells.
Moreover, other studies have indicated that, in children, myopic eyes showed a trend of choroidal thinning, while non-myopic eyes showed a trend of choroidal thickening [ 59 , 60 ].
A pre-specified subgroup analysis also showed a trend toward longer DFS in the nivolumab arm.
Both trials showed a trend towards gefitinib being initially superior to chemotherapy before the crossing of DFS Kaplan-Meier curves to favour chemotherapy after approximately four years ( 32 , 34 ).
Currently, there is not sufficient data to reach a definitive conclusion—although hypertonic saline showed a trend towards lower mortality and a more beneficial effect on CPP compared to mannitol, there were no statistically significant differences in mortality and neurological outcomes between hypertonic saline and mannitol administration [ 14 ].
Yang et al 12 reported that overall Th1 cell counts are not significantly higher in patients with glaucoma versus controls, but patients with glaucoma showed a trend toward the decreased frequency of CD4+/CD25+/FoxP3+ Treg cells within the entire CD4+ cell population.
Study eye data showed a trend toward VA stabilization at 18 months.
The evaluation of the results showed a trend toward a worse outcome amongst women with lower P4 levels and in those with higher values (delivery rate for P4 < 10.7 ng/mL: 26% versus 43% for P4 between 10.7 and 15.7 ng/mL versus 31.4% when P4 is over 15.7ng/mL).