Barely Significant
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“showed a trend”

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In the literature

The nutritional support intervention showed a trend toward a beneficial effect and lower risk of 30-day mortality in patients with high tryptophan levels (adjusted HR 0.61 [95% CI 0.29–1.29, p 0.195]), but not in patients with low tryptophan levels (adjusted HR 1.72 [95% CI 0.79–3.70, p 0.169]) ( Figure 3 ).
While these data showed a trend towards lower expression of β1-p.C89 protein in mouse brain compared with WT, there were no significant differences between average values. β1 and β1-p.R89C polypeptides localize to the plasma membrane and are substrates for regulated intramembrane proteolysis in heterologous cells Localization to the plasma membrane is required for VGSC β1 subunit-mediated channel regulation and cell adhesion.
In May 2008 the company reported, that although TOLAMBA showed a trend towards a reduction of the symptoms of ragweed allergic individuals relative to placebo, no statistical significance was achieved ( https://investors.dynavax.com/news-releases/news-release-details/dynavax-tolambatm-chamber-study-misses-primary-endpoint-company ).