Co-culture with non-transfected MSCs in the presence of cortisone, or with cortisol treatment alone, also showed a trend towards decrease in inflammatory cytokine release, however these did not reach significance ( Figures 3A, B ).
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Of the two RCTs studying fibrin, treatment with Adhexil TM showed a trend toward improved adhesion prevention (mAFS); however, the difference was not statistically significant [ 52 ].
In the age subgroups, the younger group (<75 years old) showed a trend toward better outcomes than the older group; however, there were no statistically significant differences in the median PFS and OS between COMB and MONO (PFS: 6.5 vs. 13.6 months, respectively [HR: 0.79; 95%CI: 0.55–1.12; p Value = 0.21]; OS:16.6 vs. 35.3 months, respectively [HR 0.67; 95% CI: 0.45–1.02; p Value = 0.051]) (Figure 4 ).
The small exploratory analysis also showed a trend towards improved ORR and longer PFS in patients with higher (≥1%) programmed death ligand 1 (PD-L1) expression on tumor cells 13 .
However, the combination of suPAR and CysC resulted in a significantly improved diagnostic performance compared with standard urinary parameters and showed a trend toward superior performance compared with serum creatinine, CysC, and Sequential Organ Failure Assessment score.
Preliminary results showed a trend of tissue‐specific asymmetric gene expression for paired genes belong to two sub‐genomes (Figure 1i ).
In contrast to the negative control group, the experimental group (CELLADEEP Patch) showed a trend of 27.75% decrease (improvement) in skin moisture loss at the 24‐h post‐UVB exposure time point.
Confocal line-scanning microscopy of calcium signaling in the cells showed a trend of increased calcium peak intensities for RYR2 Het KO cells vs.
The results of the period effect analysis indicate that the risk of PF in the overall, male, and female populations showed a trend of initially rising, declining, and then rising again, with the lowest cohort effects in 1992–1996 for the overall and male populations (RR = 0.9, 95% CI, 0.89 to 0.9; RR = 0.9, 95% CI, 0.88 to 0.9) and in 2002–2006 for female populations (RR = 0.9, 95% CI, 0.9 to 0.91).
Besides, randomized PRECIOUS study showed that pertuzumab retreatment in combination with trastuzumab and chemotherapy (TC) significantly improved PFS and showed a trend towards better OS than TC in patients previously treated with pertuzumab [ 10 ].
In present analysis, cases of small tumor burden in the lung showed a trend of higher prescribed BED 10 , ranging from 112.5 to 180 Gy, compared to those of large tumor burden, ranging from 76 to 87.5 Gy, and metastatic tumor burden was determined to be an independent factor for prognosis [ 29 , 36 , 38 - 40 , 42 , 45 , 46 ].
A linear function was fitted through the peak response for each cell, to determine whether evoked responses showed a trend to increase or decrease with trial number.
Soluble protein (SP) The SP content of pickled peppers in the D and G groups both showed a trend of first increasing and then decreasing ( Table 1 ).
It can be seen that with the increase of the cycle, the resveratrol yield showed a trend of firstly increasing and then levelling off, and the resveratrol yield reached an equilibrium of 3.37 ± 0.06 mg/g when the extraction cycle was 3 times, and the active ingredient had been sufficiently crushed and flowed out, and in order to save the cost of the test and the time, the extraction cycle was selected to be 3 times. 4.
Freeze-thaw temperatures showed a trend of decreasing and then increasing with time.
The SCORAD index, EASI 75/90, sleep disturbance score and pruritus visual analogue scale (VAS) showed a trend towards improvement.
The cutoff value was set at 28.84 g (Figure 1 ). The Ex group showed a trend toward improvement in the pain-response thresholds compared to the No-Ex group.
Although the tubulitis (t), total inflammation (ti), transplant glomerulopathy (cg), and C4d deposition (C4d) scores showed a trend towards higher values in the high cfDNA group, the differences did not reach statistical significance.
Prior experience and training in BPSD showed a trend towards higher scores.
Although patients combined with PTPN11 mutations showed a trend toward improved outcome compared with PTPN11 wild-type, the difference was not significant (Fig.
INF-γ showed a trend towards a protective effect; as the IMT-M decreases, there is an increase in the expression of INF-γ, and a higher proportion of subjects with elevated INF-γ concentrations demonstrated normal IMT-C.
Ra-223 treatment showed a trend towards reduction in the number of GFP-labeled osteoblasts at 1 week after treatment ( Figure 2 A–C).
In the subgroup defined as positive for PD-L1, treatment with atezolizumab plus T-DM1 showed a trend towards improved PFS compared to T-DM1 plus placebo.
coli/Shigella , showed a trend toward early expansion, thus suggesting their selective outgrowth post-transplant.
Further, a Polish sample of patients undergoing coronary artery bypass grafting showed a trend towards increased 30-day mortality with higher copeptin levels [ 40 ].