“trending towards significance”

We observed upon quantification of the ratio of H3K27me3 to H3 in a set of biological triplicates that 2i mESCs treated with Chiron-124 lost 39% global H3K27me3 modification, trending towards significance ( S8 Fig ).

Moreover, individuals who converted from A+T- to A+T+ showed an interaction effect of baseline Aβ laterality on tau laterality over time, only trending towards significance at Braak III-IV (β = 0.081, 95%CI = [0.015; 0.147], p Bonf = 0.051) and V-VI (β = 0.093, 95%CI = [0.014; 0.171], p Bonf = 0.061).

The authors combined those taking three drugs—citalopram ( n = 24), trazodone ( n = 64) and sertraline ( n = 37)—that were trending towards significance into one category, the so-called “antiviral serotine reuptake inhibitors” and found that there was greater protection from detectable HIV RNA in the CSF (OR: 0.56, p = 0.02).

For the proportion of reported values meeting at least 7,500 steps/day, significant negative correlations were apparent with changes in total cholesterol and triglycerides, while the negative correlation with change in glucose was trending towards significance (r = −0.16, -0.15, and −0.13, respectively).

We found that lower levels of CCDC122 and NUDT15 and higher levels of PVT1 , RPL30 , TRMT12 , and UBR5 were significantly associated or trending towards significance while associated with poor PFS in PCa of mixed origin ( Figure 5A , Supplementary Table 5A ).

88%) between cases and controls were not statistically significant but was trending towards significance.

In cases where there is a reduction in model performance, but the relationship remains trending towards significance, we expect the augmentation of models across perturbations to be beneficial in terms of improving results generalizability.

We found that 10 days after the booster, the levels of IgG1, IgG2b, and IgG3 were significantly higher in the CCR7 −/− mice than in WT mice, and levels of IgG2c were trending towards significance as well.

We showed comparable findings with imaging normalization (i.e., transmural healing) associated with larger minimal lumen diameter and trending towards significance for the lower max/min ratio.

The chosen model (Model B) revealed, after stepwise selection, two complement proteins, C3 and C4, as significantly different between the FEP and control groups, with four complement analytes (C5, TCC, C1 inhibitor and FHR125) trending towards significance and strengthening the model.

Patients who were younger at disease onset (r = 0.38, p = 0.054) and had a higher T1-weighted lesion volume (r = −0.32, p < 0.10) had lower accuracy on the GNG task, trending towards significance.

Additionally, none of the interaction terms were significant (first-time parent status interaction: p = 0.391; education interaction: p = 0.365); however, the interaction between pregnancy planning and prenatal mental healthcare utilization was trending towards significance, in that those who endorsed planned pregnancies and prenatal mental healthcare utilization had more severe depressive symptoms compared to those with unplanned pregnancies and prenatal mental health utilization (β = −2.48, 95% CI [−5.01, 0.05], p = 0.055).

Furthermore, performance of the PDxBR clinical versus PDxBR AI-grade model was not statistically different ( p = 0.076), although trending towards significance.

A caveat to these analyses is that the sample size is small, and additional rank order splits of the data were only trending towards significance, but similar to what has been seen before for large numbers of large scale changes [26] , [27] , tumors with the most numbers of changes tended to show worse survival.

However, employment status was trending towards significance.

Nevertheless, the clear failure of the experimental manipulation likely excluded that possibility as well, with no statistical test results for difference between groups trending towards significance.

Additionally, while isoniazid supply shortages were only trending towards significance in association with low prescription rates, nearly a quarter of our participants reported not having TPT medications available when needed.

For this reason, alpha = 0.2 was chosen as an alpha cut-off for trending towards significance, and 0.05 for statistical significance.

However, when statistical analysis was conducted on the subset of patients with LGGs, only T1 differences were significant, with T2 trending towards significance [ 107 ].

We observed cases to have significantly higher capillary density loss and higher microhemorrhages (trending towards significance) compared to controls.

Further, the mild-severe subgroup had 500 Hz and 1000 Hz source locations located more anteriorly (i.e., more disrupted compared to the control group) compared to the mild-moderate group, although this was trending towards significance only for the 500Hz left hemisphere source.

After Bonferroni correction for five seeds, only the bilateral precentral and postcentral gyri retained a significant difference in mean parameter estimates between ASD and TD groups; the right superior parietal lobule was trending towards significance (Fig. 1B ).

While differences in emergent status of the case and need for post-operative ERCP between the four and three-port RC techniques trending towards significance, no other statistically significant differences were noted between the groups (Table 3 ).

Additionally, both groups showed decreased IMAT with the difference between groups trending towards significance.

An increase in macromolecules at 0.9 ppm trending towards significance has been reported previously in response to a pro-inflammatory 1 mg/kg LPS dose in developing rats 18 .