Excerpts

Although the results were not statistically significant, our analysis showed a trend with a better PFS in patients with a higher SUV max at basal PET ( p 0.062).

Regarding Ann Arbor Stage, a favorable trend was observed in stages I–II: the median PFS was 92 months in Group A vs. 122 months in Group B ( p 0.074).

All publications showed a highly significant difference between the PTR and IPT groups.

Adjuvant radiotherapy has usually been recommended in meningeal SFT, and even when no prospective study has been addressed, retrospective analysis suggests a clear trend toward significantly better local control if radiation therapy is added in the adjuvant setting.

ctrl, and the level of the WT1 expression presented an increasing trend from CR to X ( Figure 4 B), which confirm our earlier microarray-based results [ 43 ].

Discussion The increasing availability of NGS has led to the discovery of a multitude of novel mutations of, in part, indeterminate significance in AML, as well as other malignancies [ 9 , 17 ].

Kendall’s tau paired correlation coefficients (Statistica, version 13.5) between qPCR expression data for stomach, jejunum, ileum, proximal and distal colon, and microarray DM fold change data showed that 15 of the 16 correlation coefficients were positive at p < 0.05 and one correlation coefficient (microarray DM FC vs stomach qPCR) is positive, but it is borderline significant ( Table S10B ).

Furthermore, our assumption that asbestos consumption in earlier periods was equal to that estimated for 1946 has to be considered a limitation of the study, according to the plausibility of an increasing trend between 1920–1946, although including a linear increasing trend for the period 1881–1946 does not significantly affect model forecasts ( Figure S2 , model A4).

As apparent from Figure 6 C,D, this rise of about 50 ps in 80 min is almost insignificant.

The mean levels of uPSA were lower in patients compared to healthy individuals, with a negative trend for the increase in tumor stage.

This difference was highly significant against solvent and TMZ for all timepoints, as well as against calcitriol-single-treatment after 10 days of treatment, suggesting a potential synergism.

For example, some studies showed a trend towards depletion in bacteria in adenoma cases from Fusobacteria taxa, as well as from phylum Proteobacteria (e.g., Escherichia coli , Escherichia-Shigella ) and Firmicutes (e.g., Lactobacillus ) that were commonly reported to be enriched in other studies.

The study did not achieve the expected statistical significance for shortening adjuvant treatment duration from 6 to 3 months, in CRC patients; however, there was a clear trend for patients with lower risk CRC (T1-T3/N1) to benefit from the administration of CAPOX for three months [ 6 ].

Maximum dose percentage and D0.33cc to the proximal bronchus was significantly higher with UCLT, however only a statistical trend was observed regarding D4cc and maximum point doses ( Table 3 ).

The CD8 + cells showed a trend toward increased number in the MNU-treated group (423 ± 35 cells/mm 2 ) than in the placebo group (142 ± 13 cells/mm 2 ) , but this difference was not statistically significant ( p = 0.935) ( Figure 2 f, right panel).

presented the highly significant and sensitive performance of PSMA as a histopathological marker for disease staging and the discrimination between low- and high-risk, as well as a positive correlation with the Gleason score.

CD8 + T cells from Cat-Tg mice showed a trend towards increased levels of PD-1, but had no differences in CTLA-4 expression compared to CD8 + T cells from WT mice.

It was also shown that there is a strong correlation between OPN expression and nuclear β-catenin, with a highly significant relationship between co-expression of OPN and nuclear β-catenin and a poor prognosis.

In line with our gene expression analysis, resistant cell lines showed a trend of higher JAK1 and FGF10 expression compared to sensitive cell lines ( Figure S7a,b ).

A comparison of these results with a random walk model indicated highly significant differences between experiment and simulation.

A borderline non-significant association was reported between EVTF activity and VTE in patients with pancreatic cancer but not in patients with brain, stomach, and colorectal cancer [ 69 ].

Again, highly significant differences between the cell lines were seen ( Supplementary Figures S2 and S3 ).

Interestingly, although not reaching significance, we observed a clear trend showing that the presence of nNav1.5 had a negative impact on PFS when analysed in combination with all the other biomarkers.

The exponential filter intensifies low-amplitude variations in the image, enabling the better distinction of subtle regions that might be significant for radiomic analysis.

Furthermore, by considering lymph node metastasis in the p53 aberrant GAC, a better prognostic stratification was achieved which finally allowed us to separate the GAC highly significant in a group with poor and good-to-intermediate prognosis, respectively.