Barely Significant

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Summary of Treatment Rankings and Comparative Efficacy IV iron therapy emerges as the top intervention for most endpoints: Best at replenishing iron stores (ferritin, TSAT), reducing HF hospitalization risk (high-quality evidence), provides clear improvement in exercise capacity (moderate evidence), and may reduce CV mortality slightly (moderate evidence, borderline significance).
While dialysis vintage showed a trend toward increased CI with longer duration (88.9% in patients on dialysis for more than 72 months vs 69.8% in those on dialysis for less than 24 months), this association did not reach statistical significance (χ2 = 2.38, df = 2, p > 0.05).