Barely Significant

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As expected, and similar to our data in APOE4 primary microglia, PLIN2 protein content in the forebrain of the nanoparticle F12511 -treated group exhibited a decreasing trend compared to the PBS-treated group in both APOE3 and APOE4 mice, suggesting a reduction in neutral lipid droplet content in the brains of these mice.
Only one variant, rs1695 ( GSTP1 ), showed a trend toward a significant frequency difference between MacTel cases and controls, suggesting that it is a possible modifier but not a causative gene for MacTel ( Figure 3 , Table S1 ).
Genetic Background of Macular Telangiectasia Type 2.
Int J Mol Sci · 2025 · PMC11765629
However, the content of HJ showed a trend of increasing, then decreasing, and then increasing again, and as the fruit matured, the content of QJ and CJ gradually decreased to 1.25 μg/g and 0.75 μg/g, but the malic acid of HJ was maintained at 3.45–3.87 μg/g, which was 2.76 times and 4.60 times higher than that of QJ and CJ, and it was the main reason for the acid content of HJ being higher.