Barely Significant

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Although weight loss alone may be insufficient for maintaining skin disease remission in obese patients with psoriasis [ 55 ], some recent intervention trials have demonstrated that treatment with a low-energy diet showed a trend towards significant improvement in PASI scores among overweight or obese patients with psoriasis, and that body weight reduction in psoriatic patients receiving either low-dose cyclosporine or biologics increased the efficacy of these drugs [ 56 , 57 , 58 ].
A clear trend is that at the low solvent temperatures the protein has higher numbers of internal HBs than at the high solvent temperatures, although lowering the protein temperature (when the solvent temperatures remain unchanged) can still increase the HB number, e.g., 6.3 from P300/S180 to P180/S180 and 13.4 from P300/S300 to P180/S300.