Excerpts

In this umbrella review, the recessive models of rs11614913 showed a highly significant association with OC risk.

showed that in addition to a better functional class, successful PVL closure was demonstrated to reduce cardiovascular mortality (OR = 0.08, CI95% 0.01–0.90), with a positive trend in the overall mortality, and it also reduces haemolytic anaemia (OR = 9.95, CI95% 2.10–66.73) [ 30 ].

Our study evidenced that serum IL-6—as an important promoter of inflammation—levels determined on the day of admission showed an increasing trend through higher IS tertiles.

Although not statistically significant, these pooled results showed a trend of higher complications observed in the M flap group.

Consequently, there was a statistically significant increase of the patella shift in unloaded conditions when patients with PFI were compared to volunteers with healthy knees from 0° to 15° knee flexion and a statistical trend in 30° flexion.

All of the individual statins examined showed a trend of a reduced risk of variable magnitude without differences regarding lipophilicity, while moderate and high intensity of treatment seems to present a greater effect.

Association of Statins with CRC by Active Principle, Lipophilicity and Intensity By active principle, we found a trend of a reduced risk with the current use of all statins, albeit statistically significant results were only reached with simvastatin (AOR = 0.86; 95% CI: 0.80–0.93) and rosuvastatin (AOR = 0.58; 95% CI: 0.41–0.83), being marginally significant for atorvastatin (AOR = 0.92; 95% CI: 0.84–1.00; Table 3 ).

However, despite the reduced number of patients, the analysis suggested a clear trend towards a greater PFS and OS in the pro-immunogenic group, as might be expected.

Interestingly, PSBM9 was not selected under our criteria but almost reached statistical significance in our study (FDR = 0.01 and log 2 Fold Change = 0.96, upregulated in the pro-immunogenic subgroup) which suggests that our biomarker filtering criteria could perhaps be reassessed in order to identify additional genes with potential as biomarkers.

Tumors defined as pro-tumorigenic showed a trend to accumulate certain molecular aberrations and were found in a higher proportion of relapsed patients.

Nevertheless, COP patients showed a trend toward fewer permanent ECG changes after TAVR supporting the previously seen decrease in conduction disturbances.

Of interest is the finding that the MAP < 91 mmHg group also showed a trend toward longer exposure to hemodialysis, as well as a trend toward a longer waiting time before transplantation.

The Cox regression with time-dependent covariates showed similar results, except for the association between congestive heart failure and death, which was marginally significant with the logistic regression and significant with the time-dependent Cox model ( Table S2 ). 3.7.

It should be emphasized that the LD patients had not shown any improvement with patching for 6 months; nevertheless, in the PL training, the mean BCVA increased from 0.63 ± 0.11 to 0.32 ± 0.09, with an improvement of 0.31, and the AULCSF in the CS increased from 0.49 ± 0.15 to 1.06 ± 0.20, which is encouraging and reveals a positive trend for the PL group.

Age showed a significant trend in the multivariate analysis.

In the various statistical models, atrial fibrillation doubled the risk of all-cause mortality, and the significant associations were fairly consistent, although only a tendency toward significance was found after we adjusted for body mass index in addition to the other cofounders.

Only delirium was trending towards significance in the CEPD group.

In contrast, the quantity of CEC in the control group observed on a quarter of polycarbonate membrane filter increased after the therapy from 2.0 ± 0.3 (1–6 cells) to 2.4 ± 0.3 (1–6 cells), corresponding to an increasing trend in CEC level from 400 ± 60 to 470 ± 70 cell/mL ( Figure 1 A); however, this increase did not reach statistical significance ( p = 0.28).

Comparing patients with CD with active and inactive disease showed a trend of increased levels of thromboxane B2, leukotriene B4 and 9S-HODE (hydroxyoctadecadienoic acid) in the active versus the inactive disease.

Furthermore, the value of TOI showed an increasing trend upon the initiation of chest compressions but decreased from 47.8% to 46.4% during the interruption between chest compressions.

There is a clear trend linking the RULM and the RHS, with a score of 0 on the RHS equivalent to an average score of 10.33 on the RULM.

In the under-5 age group, the SMA 3a group also showed a trend towards increasing score at and after 12 months, although this was only significant at 6 months in both the RHS and HFMSE (median 6 ( p = 0.03) and 3 ( p = 0.06), respectively).

Comparing PFMT with and without physiotherapist guidance, there was no difference in leakage reduction and treatment adherence, although the guided PFMT group showed a trend towards better treatment compliance [ 46 ].

Most patients show an increasing trend in T 1ρ values.

Differences in the SN-MP, FH-MP, Y axis angle, and FHI were highly significant, confirming that they belong to different vertical growth patterns. 3.1.