Barely Significant

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There was no significant difference between the ethyl acetate fraction and the n -butanol fraction, also between the ethyl acetate fraction and the petroleum ether fraction, but there was extremely significant difference between the n -butanol fraction and the petroleum ether fraction.
Antioxidant activity of papaya seed extracts.
Molecules · 2011 · PMC6264420
While generally both influences are of equal importance, there is a slight trend visible, that the calculation of the chemical shifts at the MP2 level of theory improves the results more than if only the force field is calcuated at the MP2 level of theory, which in some cases leads to an overestimation of the secondary isotop effects with respect to the full MP2 result.