Barely Significant

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Distribution of the 822 bp mtDNA deletion among cases and controls When the subjects from both cases and controls were pooled and stratified by median number of pack-years of combined cases and controls, a subsequent linear-by-linear association test revealed an increasing trend for mtDNA deletion from non-smoking to heavy smoking groups (both p value and p trend <0.001) ( Fig. 2A ).
Both the CD4 + ∶T Reg and the CD8 + ∶T Reg ratios were notably altered in the arm receiving daclizumab as compared to saline controls with the ratio of CD4 + ∶T Regs trending towards significance and the ratio of CD8 + ∶T Regs demonstrating a significant increase in the average percent change from baseline (p = 0.0757 and p = 0.0153, respectively).
Although several nutrients were associated with risk of CE in the basic multivariate model, most notably monosaccharides and fiber in both men and women (both negatively), no nutrients retained significance in the full model, although the protective fiber association in women was of borderline significance ( p for trend = 0.067).