Barely Significant

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highly significantqualifiedgold
It has been clarified that there is a highly significant correlation between Gd-EOB-DTPA uptake and OATP1B3 expression in HCC cells and/or normal hepatocytes, and also between the grade of OATP1B3 expression and the enhancement ratio (signal intensity) during the hepatobiliary phase of Gd-EOB-DTPA MRI [ 19 , 20 ].
This ‘point’ estimate reduces the external validity, as there is likely to be significant variance in both admission numbers of patients presenting to hospital and clinical practice on a day-to-day basis and also does not compensate for known seasonal variations in incidence of the condition.