Excerpts

In our data sets, LRPPRC expression was significantly upregulated in RC disease muscle and showed marginally significant downregulation in RC disease FCLs.

Whereas in forced luciferase experiments, KCl treatment effect was not that significant such that we did not observe a highly significant decrease in the promoter activity of SUMOylation induced Elk1 overexpressing cells ( Figure 6A, F 2+Elk1+KCl) compared to control (F2).

Interestingly, although susceptibility allele of CASP3 showed a trend of correlation with Kawasaki disease in the Taiwanese population, P -value suggested a marginal association.

71%, F (1,35) = 3.38, p = .07, η 2 p = .09) just failed to reach significance when using the correct item score.

PDGF showed a trend to increase in Eng +/+ mice at early times (4 weeks), with increases in both strains at later times ( Figure 5 ).

Hence, an increased branching frequency is the only highly significant consequence of racA disruption, which, however, does not per se result in higher protein secretion rates.

These highly significant results are also robust because similar results are obtained with different clustering methods (see [24] , [25] ).

Simple Bonferonni correction results in borderline significance for the DNMT3L effects but we believe that this adjustment is too conservative.

WTAR scores and age also did not differ significantly (p>0.12; Table 1 ), but there was a weak trend toward higher WTAR and lower age in the ISO group.

By contrast, the needle leaf litter showed a trend to decrease, increase, and then markedly decrease when the rainfall intensity increased gradually from 6.7 to 115 mm h –1 .

When the duration of aspirin use was divided into two subgroups (<5 years and ≥5 years), we observed a suggestive trend of decreasing risk of gastric cancer associated with increasing duration of aspirin use (RR = 0.95, 95% CI 0.76–1.14, for <5 years; RR = .67, 95% CI 0.56–0.79, for ≥5 years; Figure S2 ).

The line factor was significant in a few cases but the line by temperature interaction was highly significant for all traits in both sexes implying a significant contribution of the genetic factors to total phenotypic variation ( Table 1 ).

The GA combination also shares a highly significant, strong dominant effect on generating MASP-2 levels higher than 600 ng/mL with four other minor alleles: g.4847C in the promoter (rs7548659), g.21081T in intron 9 (rs17409276), g.21370T or p.371D in exon 10 (rs12711521) and g.24762C or p.S493 in exon 12 (rs1782455) ( Table 1 ).

Patel at the 2010 ASCO meeting in Chicago showed a trend toward response and clinical benefit in the patients treated with MEK 1/2 inhibitor and harboring a BRAF V600E gene mutation [11] .

HPX levels in subject plasma showed an overall trend of lowered expression in those with active cirrhosis compared to controls, with a “bounce back” effect seen as the protein levels are somewhat restored to control levels in the HCC subjects.

This makes it very difficult to carry out a fair correction so we have left the statistics uncorrected and chosen a relatively conservative threshold of P ≤0.01 for significance, and the interval 0.01< P ≤0.05 as marginal significance worthy of discussion.

Four of them were at the margin of significance, with two (towards the left end of chromosomes 2 and 8) slightly exceeding and two (one at the left end of chromosome 1, the other at the right end of chromosome 9) nearly reaching the threshold; while all others were apparently under the threshold ( Figure 1B ).

Average leg orientation IMA showed an increasing trend with smaller targets and showed a significant increase between the large and small target conditions (F(2,30) = 4.675, p = 0.02, Figure 4 ).

There was also a highly significant association between the phase of HBV-infection and liver cirrhosis detected by ultrasonography during follow-up.

With the Q 2 value within the excellent range, close cross validation, response permutation significantly below the maximum values allowed, and all the variables used highly significant with similar relevance to the model; as well as the regression line of the training set with RMSEE of 3.5, coupled with the R 2 value of 0.9779 and RMSEP of 3.8 for the test set indicates that this is a very good model, see figure 3 .

Analysis of variance (ANOVA) was applied to ascertain the significant of differences, and the p-values less than 0.05 were considered as significant (*) and the p-values less than 0.005 were considered as highly significant (**).

Notice that the red and purple types showed a trend of negative Tajima’s D values even if they did not reach statistical significance ( Table 5 ).

The SNP rs876538 showed nominal significance in analysis of all cases; and the additive risk score was nearly significant with a Bonferroni adjusted p value of 0.009, whereas rs2794521, rs3091244, and rs3093068, demonstrated only marginal significance ( P = 0.068, p = 0.078, P = 0.063 respectively) in univariate analysis.

(For example, the main effects model estimates the odds of achieving reading fidelity to be about three times as high for the SPACED condition as for the NORMAL condition.) We observed a marginally significant main effect of device (POD being better).

The fact that our finding only showed a statistical trend narrows its relevance, however.