There is no consensus on how p-values should be estimated for linear mixed models, but following the t-statistics obtained from using the Satterthwaite’s method, the effect of the participant’s role (whether proposer or recipient) was highly significant (p < 0.0001) whereas the effect of the depression diagnosis and the role:depression interaction were not.
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The results in Table 7 demonstrate a highly significant difference among algorithms ( P <0.0001), substantiating the robustness of bDTOPRS in feature selection.
The coefficients for an unassigned genus of Bacteriaceae and for the genera Blautia , Dorea , Clostridium , Fusobacterium , Oscillospira , Phascolarctobacterium , Slackia and Streptococcus were highly significant (P<0.0001, S6 Table ).
The differences in Ln probability of the data between the two most likely scenarios (#1: length-at-age as prior, k = 2 and #2: sampling location as prior, k = 2; Fig 4 ) were highly significant (Steel-Dwass All Pairs, z = 5.7, p <0.0001).
These regressions persisted when adjusting for age, UPDRS III or LEDD in a multivariable regression analysis, as time from diagnosis remained a highly significant negative predictor of CSL (R = 0.66; slope ß = -0.029; p < 0.0001) and a positive predictor of CCAD (R = 0.57; slope ß = 0.033; p = 0.0002), while age (CSL, slope ß = 0.003; p = 0.63; CCAD, slope ß = 0.001; p = 0.94), UPDRS III (CSL, slope ß = 0.32; p = 0.09) or LEDD (CSL, slope ß = 0.23; p = 0.22) were not predictors.
Intriguingly, the sorted IFNβ + Tip-DCs also stimulated the naïve T cells to proliferate in a highly significant manner (p < 0.0001 as compared to macrophages) and more efficiently than the sorted IFNβ/YFP − bona fide Tip-DCs ( Figure 6 ).
Moreover, during development, these offspring showed a markedly greater increase in body weight, demonstrating an apparent trend toward obesity ( P < 0.0001) ( Fig 2b ).
The one-way ANOVA conducted for testing significance of the mean iH O among the six populations investigated was highly significant: F 5,172 = 31.92, p < 0.0001).
We found a highly significant association between signal in the DCR6 and escape bias overall (main effect of phenotype p<0.0001, with significant within-genotype effects after controlling for multiple comparisons in CaSR +/+ and CaSR p190/p190 groups) ( Fig 4A ).
Statistical analysis of the data performed in the three groups confirmed the presence of a decreasing trend over time in this difference in the CF group (p<0.0001) and the increasing trend in the non-CF (p<0.0001) and in the HTZ (p = 0.04) groups.
All prevalence rates for all cancer types when compared with the fracture group were highly significant (p-value <0.0001).
The suppressive effect of Zolpidem on the frequency of calcium transients was consistent across sessions within the identified inactive periods, and this effect was highly significant in the data combined across sessions (WSR test, p<0.0001, n = 943 cells, Fig. 3C ).
Mean FID in the 714 populations ranged from 1 to 180 m, mean (SE) = 11.46 m (1.03; back-transformed from log 10 -transformed data), with a highly significant effect of species ( F = 3.06, df = 158, 555, R 2 = 0.47, P <0.0001).
There were no significant differences with gender and there was a weak but highly significant positive correlation with age (Spearman rho = 0.205, p<0.0001).
When comparing “periphery” and “interior” patterns, the difference in radial distribution of DAO-5 was highly significant (Mann-Whitney test, p <0.0001).
The resulting linear regression equation, optimized for Amemiya Prediction Criterion, is highly significant (correlation coefficient = 0.787, r - 2 = 0.606 , P<0.0001, α = 0.05, see Fig 14 ).
Unless otherwise stated, all the relationships reported are highly significant ( P <0.0001).
As shown in Fig 1A and 1B , a highly significant effect (p < 0.0001) was found in different PL concentration ranges tested in MM-231 and MM-468 cells.
In addition, our results show that the S-pillar has a positive and highly significant (p-value < 0.01%) impact on ROA.
Each term in the model (coverage, month, and region) was highly significant ( P < 0.0001) and provided significant explanatory power [ 16 ].
There was a highly significant correlation (P<0.0001) between rice content and inorganic arsenic concentration across all infant foods.
As for night-time, wakefulness during daytime, occupied the highest proportion (60.4 ± 1.8%) compared with the percentages of drowsiness, NREM sleep and REM sleep (9.4 ± 0.8%; 23.4 ± 1.5% and 6.7 ± 0.6%, respectively) and these differences were found to be highly significant (p < 0.0001; p < 0.0001; p < 0.0001) ( Fig 5C ).
There was a highly significant positive correlation between hepatic cellular infiltrates and the copy number of dnTGFβRII transgene (r = 0.9342, p<0.0001), indicating that abrogation of TGFβ signaling by higher copy number of dnTGFβRII contributes to the emergence of T cell lymphoma-like T cell infiltration.
There was a significant trend towards an increasing use of VATS over time (χ2 = 41.85, P <0.0001; Figure 2A ).
ANOSIM detected highly significant differences in meristic counts between intensive and organic lots (R = 0.04; p<0.0001).