The number of patients with a systolic blood pressure (SBP) >140 mmHg decreased from 70.1% to 42.0% in men, and from 80.2% to 40.3% in women (p for trend in both sexes <0.001), whereby a small trend difference between sexes was observed due to the difference in the first years (p for interaction <0.001).
The long-term impacts of koala overbrowsing on the ecosystem are poorly understood but also likely to be significant.
These changes trigger a bottom-up effect on key biological traits of T evansi causing a highly significant increase of leaf damage and mite performance.
All variables show highly significant associations with CM, which increased with age; decreased with flock size; was highest in flocks of intact beaked birds and organic flocks; and varied with both housing system and breed.
Considering published studies, time-to-publication showed a decreasing trend over the years.
Glycosaminoglycans carry densely packed negative charges and as a result there may be significant osmotic shifts associated with compression, leading to stiffening.
Ets2 knock down had a suggestive but not significant effect on proliferation in Ts cells ( Fig 4A ).
Although the brain infarction showed a trend toward reduction following low-dose (25 mg/kg) and high-dose (100 mg/kg) administration, there was no statistical significance reached (25 mg/kg, 24.7±3.0%, 100 mg/kg 24.6±4.8% vs.
Regarding personal factors, we discovered a significant trend of LTCF residents with a higher education level having higher scores in SOC and its three core components.
Other studies have shown that underreporting may be significant and more frequent among groups for which suicide is culturally unacceptable, or it may be higher for women who die by drowning or poisoning, or in general from accidents or violent deaths for which intentionality cannot be established [ 60 , 75 ].
A clear trend can for instance be observed for the effect of remifentanil when administered by target-controlled-infusion (TCI) of anesthesia ( Fig 3(C) ): for total doses below 5 g there is a nearly linear trend towards a higher risk of PONV.
Between-subject random effect (η) for maternal CL is correlated with maternal heart rate with an overall trend of higher η associated with higher heart rate ( Fig 4 Panel A).
It has been suggested that the considerable heterogeneity of study populations and study methodologies in the current literature might be significant reasons for this diversity of study results [ 7 ].
Therefore, given the small sample size and the lack of an obvious trend we assumed that n was independent of N / K , and described the variation in n based on a mean rate of ground disturbance recovery of 2.4% per annum, with a standard deviation of 1.5% ( Fig 5B ).
In addition, a decreasing trend in the odds of anxiety and depression was seen with increasing scores of healthy lifestyle.
P < 0.05 was considered significant and p < 0.01 was considered highly significant.
The amount of Al ( Fig 5B ) and V ( Fig 5L ) were significantly increased in smokers (p = 0.028 and p = 0.032, respectively) and there was a clear trend for Ni, Cr and Pb ( Fig 5J, 5I and 5N , respectively) that didn’t reach significance.
The expression levels of PLOD1 was significantly increased in both AF-S and AF-nS clones under TGFβ3 conditions; all three PLOD genes showed a trend toward higher expression in AF-S clones ( Fig 5 , middle left panel).
Within 4 and 6 days of culturing, a clear trend towards significantly different COL1A1/ProCOL1A1 ratios between AF-S and AF-nS became apparent ( Fig 4C ).
If we check the effect of the text length L in the distribution of β , we find a decreasing trend of β with L , as can be seen in Figs 9 and 10 .
ETE MOIs showed a trend of reaching further distances in both X and Y directions, which is also confirmed by the volume occupied by these MOIs.
In terms of movement laterality, highly significant differences were found in terms of the movements characteristics, as it can be depicted in Table 3 .
A priori, we postulated that as an overall trend cost-effectiveness would tend to be more favorable in the early phase of the adjuvant setting than in the late phase of metastatic treatment.
The aim of this study is to identify a possible trend in the cost-effectiveness for the early/adjuvant and late/metastatic stages of oncological drugs through review and case study.
Though not significant, there was an unexpected trend towards increased healthy muscle area (HMA) of all thigh muscles by 6.2% ( Table 3 ).