Barely Significant

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Correcting for multiple testing using q-values based on Benjamini, Krieger, and Yekutieli (2006) [ 24 ] did not change any of the conclusions about statistical significance; corrections using q-values based on Benjamini and Hochberg (1995) [ 25 ] did not change conclusions for six out of seven statistically significant impacts reported and showed borderline significance for the seventh (minimum meal frequency: q = 0.0519).
Later survey years (2011–2014) showed a trend towards earlier chronotypes on average based on smaller peaks (earlier MSF We ) in adolescent groups but this was not significant (linear regression model; survey year: b = -0.001, year*age: b = -0.0002, year*sex: b = -0.016, year*age*sex = 0.002, all p > 0.05).
highly significantqualifiedgold
The 395 genes with reduced expression in eWAT of Mest pKO mice showed highly significant associations with immune system processes (Padjusted <10 −10 ) including defense, immune, inflammatory and stress responses whereas genes with increased expression in eWAT of Mest pKO mice (n = 301) showed enrichment for single-organism metabolic processes (Padjusted<10 −3 ) including oxidation-reduction, organic acid metabolism; and, fatty acid, acyl-CoA, thioester and monocarboxylic acid metabolism ( Fig 8B ).