Barely Significant

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Following the trend of glomerular PMN influx, the expression of pro-inflammatory cytokine IL-6, the chemokine CXCL1, endothelial cell adhesion molecule ICAM-1, L-selectin and NF-κB was either significantly increased or showed a strong trend towards increased mRNA expression 2 hours after co-injection of anti-HS antibody EW3D10 compared to mice injected with anti-GBM IgG alone, which persisted up to 1 day after co-injection for IL-6, CXCL-1 and L-selectin ( Fig 5A–5E ).
We have amended the result to show 3 decimal places and to state that it is only borderline significant: “For “outcome expectations”, those aged 60-75 seemed more likely to have low motivations as compared to those aged 40-59, with borderline significance (adjusted OR 1.569, 95% CI 1.004-2.453, p=0.048).” We have also removed the outcome expectations from the discussion section given the marginally significant result.
It is initially recognized from Fig 3 that the number of consultations and hospital beds in Hubei province show an increasing trend year after year, which is in line with previous studies [ 55 ], and such an increase may be caused by the increasing resident population and the growing industrialization.