Excerpts

The coefficients associated with being a nurse decrease significantly and maintain only marginal significance.

The racial/ethnic disparities were large and highly significant, particularly the odds ratios for HIV prevalence among African-American compared to White subjects.

The majority of the inflammatory genes showed a trend towards increased expression with HCA ( Table 4 ).

In addition, p , p’ -DDE showed significant positive association with bloodspot TSH, and marginally significant negative association with total T3.

P < 0.05 was set as significant results, but considering small sample size, p < 0.10 was also shown as marginal significance.

When including the covariates, the year effect on bednet ownership becomes stronger and marginally significant, and the conservancy residence coefficient remains insignificant.

Nominally significant associations were observed between variations in the alpha-2A adrenergic receptor gene ( ADRA2A ) and the Slow-5 band.

We identified a significant over-expression of S100A13 in cPTCs by LC-MS/MS, ELISA, partially in WB experiments, but IHC showed very similar expression patterns in cPTCs and benign lesions with only a slight increase and borderline significance.

This in vivo confirmation may be significant as it suggests that, in vitro , these cells would show an onset response to step current injection.

Genotyping analyses suggest that the contribution of wild type cells to LAM tissue may be significant, to the extent that it can be challenging to detect the presence of a TSC-2 mutation at any level [ 15 ].

However, when a clinical correlation between the CDAI index and sema3A was calculated for each patient's group, we could find only a statistical trend. 3.

If the fold change (log2) was >1.5 or <−1.5 and the P-value was ≤0.01, then it was considered to indicate an extremely significant difference in expression levels.

Because glucose was actively transported in the intestine, intact and active sacs concentrated glucose in the serosal side, and ratio of the glucose concentration in the serosal side to that in the mucosal side exhibited an increasing trend throughout the entire experiment.

There may be significant differences of gestational fetal KCs at different ages.

Second, “type of disinfectant” and “number of humidifier disinfectant brands used” showed a marginally significant association with the risk of HDLI.

With values lower than 50 ng/ml the pectate lyase specific IgE levels of Italian patients were generally low; nevertheless there was a clear trend towards increased binding of Cupressaceae pectate lyases compared to pectate lyase allergens from Asteraceae. 83.3% of the Italian patients reacted with Jun a 1, 60% with Cup a 1, 86.6% with Cry j 1, 26.6% with Amb a 1, and 33.3% with Art v 6.

Fig 3 again supports our hypothesis that a smaller subset of similar patients comprises a better training dataset (i.e., both AUROC and AUPRC showed an increasing trend moving left on the X-axes).

Interestingly, control males showed no decline in resting metabolic rate with age, whereas it declined significantly in the rapamycin-fed group ( Fig 3F ), thus there was a highly significant Treatment X Age interaction ( p < < 0.001) in males.

Interestingly, the area under the ROC (AUROC) curve of S100A9 was highly significant (0.947; 95% confidence interval, CI: 0.845–1.049).

Microbial communities Although a strong trend was observed that healthy cats formed a cluster when compared to all cats with diarrhea, this was not significant based on ANOSIM of unweighted Unifrac distances (p = 0.38; Fig 3 ).

Overall, NK cell depletion resulted in decreased expression of NK cell cytotoxicity and inflammation ( Klrc1/Nkg2a , Klrd1/CD94 , Ncr1/Nkp46 , FasL , and Tnfa ; expression of Klrk1/Nkg2d were not affected) and fibrosis markers ( Col1a1 , Timp1 , Mmp8 , and Mmp9; Sma expression did not change) (Fig 4A and 4B ); there was a notable trend toward lower levels of IL-6, with significant decreases in the concentration of Tnfa and IL-1b at 21 days ( S4 Fig ).

The mRNA expression of MTDH gene in breast cancer cells revealed an increasing trend from low to high level, as 1.11 ± 0.10 in MDA-MB-231 cells, 17.58 ± 3.11 in MCF-7 cells, 49.66 ± 10.77 in MDA-MB-435S cells, and 201.74 ± 14.57 in MCF-7/ADR cells ( Fig 1A ).

During the progression course from grade II or grade III to grade IV (GBM) we found a strong trend for mTORC1-signaling induction, which supports the notion of mTORC1-activation as a driver for tumor progression.

Fas ligand on the other hand was comparably rarely expressed with 0.94 ± 0.69% in cells with mild degeneration and showed a trend to slightly higher expression in cells from severe degeneration samples (5.06 ± 4.12%).

As expected, estrogen showed a trend of BCL2 induction and progesterone significantly induced MYC expression ( Fig 7A ).