An multinomial logistic regression analysis indicated that for overall developmental levels, being at the normal level was influenced by increased family income and decreased parental age (borderline significance at p = 0.052).
For IL-1β, the overall difference between groups was borderline significant (global unadjusted p = 0.052; age-adjusted p = 0.051), with a trend toward higher medians in periodontitis (5.1-fold vs. healthy, p = 0.067; 3.7-fold vs. gingivitis, p = 0.195; Fig. 2 b).
Furthermore, the difference in RPR-T between both groups had a trend toward significance (0.21 ± 0.71 (95% CI 0.01, 0.40) D vs. − 0.09 ± 0.75 (95% CI − 0.33, 0.15) D, P = 0.052).
Similar to previous studies, group size positively correlated with gene expression, but this result was marginally non-significant (GLM: Z = 1.94, P = 0.052).
Significant positive correlations were also found between baseline CLU levels and the DAS28 at months 3 and 12 (r = 0.346, p = 0.012; r = 0.367, p = 0.007, respectively); however, the correlation at month 6 showed only a nonsignificant trend towards a positive association (r = 0.271, p = 0.052) (Fig. 2 ).
We found a significant reduction in phosphorylation levels of GSK3α/β (53.4% reduction, P < 0.001), and a borderline significant reduction in CREB (34% reduction, P = 0.052) and mTOR phosphorylation (21.4% reduction, P = 0.062) (Fig. 5 B) after 48 h exposure to 10 μM SB747651A.
6 ; χ 2 (1) = 5.55, P = 0.0184), while the interaction between music playing condition and accompaniment condition approached significance (χ 2 (1) = 3.78, P = 0.052).
Additionally, diabetes mellitus was approaching significance ( P = 0.052) Differences in structure and values of blood flow parameters among 5 groups Box-and-whisker plot of the MD, cpRNFLT, mGCIPLT, and MBRs for the five study groups are shown in Fig. 1 .
Additionally, there was a strong trend for a significant difference in PE across the three groups at d18 ( P = 0.052), with higher PE in the MFGM− group compared to the others.
This effect was further qualified by a near-significant condition-by-time-by-group (F 1,62 = 3.911, p = 0.052, ηp2 = 0.059) as well as a significant condition-by-time- by-valence- by-group (F 1,62 = 4.040, p = 0.049, ηp2 = 0.061) interaction.
Intracellular volume was borderline significant (p = 0.052) at the uncorrected level alpha = 0.05, whereas total body volume was not significant but still had a fairly small p-value of p = 0.083.
In addition, we observed a marginally significant association between the cerebello-parietal component and the number of responses from the letter fluency of the COWAT (R = 0.235, P = 0.052).
After a mean follow-up time of 42.1 months, a borderline significant benefit was found for patients with N2-N3 stage disease (HR, 0.35; 95% CI, 0.11–1.06; P = 0.052).
This significant difference was not observed with the CellSearch system (p = 0.383), while the EPISPOT assay showed a trend towards a higher CTC detection rate after RP (p = 0.052).
Comparisons between ROC curves for the modified scores compared with their original values are summarised in Table 3 , and show a significant difference for the HEMORR 2 HAGES (p = 0.028) score with borderline significance for the modified ATRIA score (p = 0.052).
The two cohorts differed statistically based on the genotype distributions (χ 2 = 13.918; p = 0.0009 Fisher’s exact test) and allele frequencies of TAS1R3 SNPs (χ 2 = 13.776; p = 0.0010 Fisher’s exact test), the diplotype distributions (χ 2 = 8.248; p = 0.0181; Fisher’s exact test) and haplotype frequencies of TAS2R38 SNPs (χ 2 = 8.566; p = 0.0138; Fisher’s exact test), and the genotype distributions of CD36 SNP (χ 2 = 6.875; p = 0.032; Fisher’s exact test), while the allele frequencies for this locus was at the limit of significance (χ 2 = 5.887; p = 0.052; Fisher’s exact test).
However, since there was a statistical trend ( p = 0.052 in the contralateral hand), it cannot be concluded at this point that scaling dysfunction is entirely independent of pain occurrence in MSA.