Excerpts

In recent years, there is also an increasing trend to apply proteomics in zebrafish for developmental analyses, disease studies and assessments of chemical toxicity.

Both changes in the expression level were highly significant ( p -values 2.5 × 10 −6 and 4.9 × 10 −6 ).

The PMCH gene is not detected significant in the ordinary regression (P-value: 0.429), but is detected highly significant in the robust regression (0.022).

The increasing trend of summer and winter precipitation over the Himalaya is associated with an increasing trend in precipitation extremes connected to the changing pattern of the summer monsoons 20 , 24 , 25 , 26 , 27 , and an enhancement in the strength and frequency of winter westerly disturbances 18 , 28 , 29 , 30 , 31 (extratropical storms driven by the Westerlies, that bring sudden winter rain and snow to the northwestern parts of the Indian subcontinent), respectively.

Concentrations for Cd, Pb and Zn show a different pattern with a decreasing trend from east to west and a northwestward tailing from S19 ( Fig. 4e ).

CTnT significantly increased 4 hours after exercise; a statistical trend was evident for POST +1.

Values are represented by the standard asterisk system where P < 0.05* is statistically significant; P < 0.01** is of medium significance and P < 0.001*** is statistically highly significant.

Furthermore, the unique faction of Env (3%) turned to be marginally significant ( Fig. 3c ).

The optimal temperature of most mesophilic methanogens is about 35 °C, with methanogenic activity showing a decreasing trend when above this temperature 33 , 34 , 35 .

Compared with the Al 3+ -treated group, the content of cAMP increased significantly when DP 1 was activated or DP 2 was inhibited (P < 0.05), whereas the content of cAMP showed a trend of decrease when DP 1 was inhibited and the content of cAMP decreased significantly when DP 2 was activated (P < 0.05) ( Fig. 7B ).

Simple effects tests to investigate group differences at each time point showed a trend where the highly significant group difference at time zero (described above) became not quite significant after two weeks and then not significant after four weeks (F = 233.5, P < 0.0001; F = 3.29, P = 0.072; F = 0.28, P = 0.60, respectively, with df = 1, 114 for all three tests).

Tsuang YH 2 found that SCs showed a trend to survive without damage under an intensity of 300 mW/cm 2 ultrasound.

Large HDL particles showed a trend of increase during SR ( P before correction for multiple testing <0.05, not significant after correction).

vaccinated or naïve control mice, a highly significant difference.

The diabetic tissues showed a trend toward reduced sensitivity to the inhibitory effect of the c-kit antagonist imatinib on phasic contractions 18 .

Still to be addressed are the physicochemical and pharmacokinetic aspects of PGH treatments [which are likely to be significant, considering the potential for intracellular transport].

In comparison, recordings across the brain in the middle and bottom layers showed a trend of increasing sO 2 .

Regarding cytokines, chemokines, and growth factors, patients with higher levels of IL-10 and IL-15 as well as lower levels of TGF-β, RANTES, and EFG had higher hazard ratios for mortality, which were marginally significant after adjusting for age (IL-10, HR = 1.013, 95% CI = 1.002–1.024; IL-15, HR = 1.146, 95% CI = 1.022–1.287; TGF-β, HR = 0.876, 95% CI = 0.770–0.998; RANTES, HR = 0.900, 95% CI = 0.780–1.015; EGF, HR = 0.9633, 95% CI = 0.9303–0.9974).

9 also reported highly significant effects for this locus using the Illumina BovineHD chip.

Moreover, we observed a negative trend for the ultimate strain versus time, attesting a general decrement of the resistance force.

We detected a positive trend versus time for the Young’s modulus, indicating that aged silks are stiffer and possibly less effective in catching prey.

Kaplan-Meier survival curves revealed a significant trend towards poorer survival for patients whose primary tumors showed low 14-3-3σ expression, compared with those patients whose primary tumors showed high 14-3-3σ expression (Log Rank = 16.351, P = 0.000; Fig. 4D ).

The results indicated that after the first two stimulations, there is a decreasing trend in the proportion of good responders and in the number of oocytes retrieved with increasing times of ovarian stimulations.

A clear trend was apparent among amino acid residues having aliphatic and aromatic side chains ( Table 4 ).

Separate from tests for gene-environment interactions, time spent outdoors itself was not associated with myopia in 3 of the 5 cross-sectional studies (GZT, STARS, and TEDS) and the association was of borderline significance in another (TEDS).