Barely Significant

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With regard to our main hypothesis, we found that during syncO, female participants indicated feeling significantly less feminine and male participants significantly less masculine than during the baseline, syncS, and asyncS control conditions; the difference between syncO and asyncO showed a significant trend in the hypothesized direction (Fig. 1 g; Tables S2 and S3 ).
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Following this analysis, we concluded that although some overfitting of the methods could be responsible for the 100% correct identification and for the high AUC values in classification, highly significant results could be obtained effortlessly and in different ways, e.g., with the ‘drift’ (total movement) of the eyes (Fig. 5 e), or even with pupil size modulation (Fig. 5 f); see the “Robustness” section above.
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With the H3K27ac ChIP-Seq, the regions showing the most highly significant differences in left ventricular chromatin from WT and Uty GT mice concerned two MSY peaks, i.e. one in the first exon region of Uty (FDR = 1.3E − 27) and one in the first intron region of Ddx3y (FDR = 1.2E − 27) (Fig. 3 ).