M8) were highly significant (p < 0.001) for each locus.
Excerpts
All variables remained highly significant ( p < 0.001) at Step 4, except for age (p < 0.05) and PQFR (p = 0.101) .
The isolates and clones exhibited highly significant differences ( p < 0.001) ( Table 1 ).
The multivariate ANOVA indicated a highly significant group effect (Wilks-λ=0.89; F(8,512)=3.9; p <0.001) and a trend for a gender effect (Wilks-λ=0.96; F(4,256)=2.4; p =0.052).
The reliability of RNA-seq data was validated by qRT-PCR detection of 10 randomly selected up- and down-CRGs using gene-specific primers ( Supplementary Table S1 ), showing a highly significant correlation (R 2 = 0.96, p < 0.001) between the results of RNA-seq and qRT-PCR ( Figure 2 C,D).
The difference between the groups was highly significant (two-sample Wilcoxon rank-sum [Mann-Whitney] test, p < 0.001).
We find that colony size has a highly significant effect on agricultural system when treated as either a continuous variable (PGLS, β = 0.12, p < 0.001) or a categorical variable (univariate multinomial logistic regression, see the electronic supplementary material, Multinomial model analysis).
The measurement loadings for all latent variables are moderately high to high (range: 0.617–0.92) and highly significant ( p < 0.001) (see Appendix I ).
When considering factor loadings and associated statistics for the best two-factor and three-factor models with sleep removed, all factor loadings were highly significant with t-value between 9.6 and 25.9 (minimum critical t value of 3.29 for P = 0.001) ( Table 4 ).
In relation to why previous GWA studies have not previously identified ABCC5 as a T2D susceptibility gene, it is worth noting that while individual nominally significant SNP p-values nearest to the estimated ABCC5 variant location at 185,136 kb for the WTCCC (e.g. rs3749441, P = 1E−03), NIDDK (e.g. rs1016752, P = 0.04) and TwinsUK samples (e.g. rs8180093, P = 0.002) do not pass genome-wide significance ( α = 1E−05), when all the SNPs in the region are considered collectively as part of a multilocus model, they do provide strong evidence of association with T2D and insulin resistance (meta-analysis P = 3E−07).
The negbin variant of count models was used as the estimated alpha parameters were greater than zero and highly significant (p < 0.001); and, the dependent variables had no zero observations.
Two highly significant interactions for Cohort by Actor Origin (F (15, 435) = 18.86; p < .001; η 2 p = .39; SE = .62; B = +∞) and Actor Origin by Emotion effects (F (18, 522) = 10.01; p < .001; η 2 p = .51; SE = .41; B = +∞) were also revealed (see Figure 2 ).
Likewise, in-hospital mortality following the first 72 postoperative hours occurred in 8 (2.7%) patients in group 1 and in 3 (0.4%) patients in group 2, which showed a statistically highly significant difference between the groups ( p = 0.001).
We found that the differences in the pretest were extremely significant [ t (63) = 31.40, p < 0.001] with respect to the social status.
In applying a convolutional neural network to estimate brain and cerebrospinal fluid intracellular volume, Qin et al [ 16 ] reported highly significant correlations (all p <0.001) between uncertainty estimations and observed error based on ground truth values.
Recovery group IV showed less improvement in Caspase expression (highly significant with group III, (P ≤ 0.001) (Fig. 11 ).
On a categorical scale, four-year hazard ratios (95%CI) for MACE were significantly higher with CS_top than with CS_low (4.82(3.39-6.85), p < 0.001), which was also the case for all-cause death, cardiac death, myocardial infarction, and ischemia-driven revascularization; for all these endpoints, there was a significant trend ( p < 0.001) for higher event rates with increasing CS tertiles as shown in Figure 2(A–E) .
The difference in methylation status of the ALX4 promoter between the patients with colorectal neoplasia and the control group was statistically highly significant ( P < 0.001).
Regarding educational attainment, the 10-years analysis showed an increasing trend in the HTLV-1/2 seropositivity for the lowest level ( p < 0.001) and for the highest level of education ( Figure 5 ).
The spatial smooth term was highly significant (edf = 37.33, p < 0.001), and the model explained 55.5% of deviance (adjusted R 2 = 0.516; Table 3 ).
Furthermore, the results on PTH gene expression among RNA seq (rlog normalized) and qPCR data showed a highly significant correlation (rho = 0.81; p < 0.001). 3.4.
At 12 months, this rose to 68% and 32% in Group I and Group II, respectively, which was highly significant ( P < 0.001) in both cases.
For Germany as a whole, the respective dummy variable is highly significant (1.094 percentage points; p < .001).
Differentiation was highly significant between the X. citri pv. citri populations from the two groves ( R ST = 0.697, p < 0.001 and F ST = 0.274, p < 0.001).
The most enriched components included the cytoplasm (56.6%), exosomes (45.5%), extracellular (30.8%), extracellular region (16.2%), cytoskeleton (15%), and extracellular space (11%), all with highly significant values ( p < 0.001) ( Figure 3 ).