Excerpts

In particular, the adjusted R 2 for the two fits in Figures 3A and 4C from [ 6 ], are respectively, 0.97 and 0.25, where F value (160) for the fit comparison is statistically highly significant (P~10 −15 ).

‡ Although the Spearman correlation coefficient between α and age is highly significant for those α values corresponding to tract density with a P value ~10 –15 , the effect size is low with a Spearman correlation coefficient of –0.06.

The differences in temporal variability are highly significant (medians for sources vs. sinks, 0.022 vs. 0.016, p < 10 −15 , two-sided Wilcoxon rank-sum test).

The correlation coefficient at 100 ms is 0.67 (n = 95) and is highly significant (p <10 −15 ).

Results A highly significant variation among all individuals and within each breed was observed in the number of duplications ( P < 10 −15 ) and in the number of deletions ( P < 10 −15 ).

Again, we found a highly significant overlap (Fig. 2 b), with 43.1% (401/931, p < 1.0 × 10 −15 ) of the HIV-responsive proteins identified here being part of the HHPID.

While there is a highly significant correlation between PC1 for both methods ( R 2 = 0.949, p < 1 × 10 −15 ), later PCs are often not significantly correlated, with the most notable exception being EFD PC2 and PH PC3 ( R 2 = 0.432, p < 1 × 10 −15 ), although several other PCs also show weak correlations.

In contrast, both adult studies showed highly significant (all P <10 −15 , matched-pair t -tests) reductions in spindle density (12% and 15% reductions in SHHS and MrOS, N =2,597 and 958, respectively), amplitude (5 and 12%) and duration (2 and 2%) across the ∼5-year period, consistent with the cross-sectional analyses.

We have to reject the null hypothesis and this result is highly significant ( p < 10 −15 ).

Our analysis of first round data indicates that while there was considerable diversity in the raw scores provided by individual participants, the inter-rater concordance was substantial and statistically highly significant (Kendall’s W=0.150, p-value < 10 −15 ).

While we estimate that this stringent quality control produced well calibrated association test statistics for more than 99% of sites, this analysis yielded many extremely significant p-values at SNPs outside of known loci (e.g. ~7,000 with p < 10 -15 ), 95% of which had an allele frequency below 5%.

First, they represent a consistent and highly significant (Wilcoxon test P < 10 −15 in all growth phases except LS) decrease in expression across hundreds of rpoS regulated genes, in all five growth phases.

The 5' ends can be seen to be much less variable than the 3' ends, a difference that is highly significant ( p < 10 -15 , Wilcoxon rank-sum).

Stepwise analysis of the multivariate model resulted in a highly significant ( F 11,1571 = 16.86, P < 10 −15 ) equation with eight additive directional terms (LINE, R.CALL, R.VOL, R.CHIRP, R.V.PULSE/CHIRP, R.V.CHIRP.W, R.IPULSE.W), one stabilizing term (PULSE, labeled as S.PULSE in the equation) and three interactions (LINExR.VOL, LINExR.CHIRP, LINExR.IPULSE.W).

One-sided Wilcoxon matched-pairs signed-rank tests (paired by subject and parcel) confirmed that these differences were highly significant ( p < 10 −15 ) across all comparisons, with SA consistently outperforming P3 and P3MT.

As previously noted, a larger proportion of pairs have a TMRCA under 8 months in Sheffield relative to London (24% versus 4%), and overall the London pairs have an average TMRCA of 4.4 years compared to 1.5 years for the Sheffield pairs, with the difference being highly significant (KWT, P < 1 × 10 −15 ).

At 2 hpi, highly significant ρ values of 0.68 ( P < 1.0 × 10 −15 ) and 0.67 ( P < 1.0 × 10 −15 ) were observed for the MAP-infected and control sample groups, respectively.

The differences in median PEN MICs were highly significant ( P < 1 × 10 −15 for all pair-wise comparisons by Mann-Whitney U test).

4 ), and this difference is highly significant (Wilcoxon rank-sum test, P < 10 − 15 ).

Shapiro-Wilks tests of Normality were highly significant ( p < 10 −15 ) for both groups, and so measures of means and variances were not appropriate characterizations of the distributions.

This is clear from gene ontology (GO) analysis of the genes associated with HOT regions: Categories such as ‘metabolic process’ and ‘cellular component biogenesis’ are highly significant (both P < 10 −15 ).

The enrichment of functionally characterized sites within the group of AcP‐insensitive sites is highly significant ( p = 1e −15 , Fisher exact test).

Analyzing the AMΦ data with linear models to control for batch effects, we found a highly significant effect of CSE concentration (p < 10 −15 ) on phagocytosis.

Due to large sample sizes, all obtained P values for context/subcontext comparisons are highly significant ( P < 10 −15 ) for all observations mentioned in our study.

Of 17,566 detected genes, we identified 1,080 highly significant differentially expressed genes upon viral stimulation (p<1.00E −15 , FDR<1.00E −14 ), including various immune function and inflammation-related genes, genes involved in cell signaling, cell regulation and transcription, and genes with unknown function.