Excerpts

Moderately differentiated and PD tumours themselves form weaker clusters ( P =0.05 and P =0.06, respectively), however when combined they show a highly significant clustering pattern ( P =0.002).

Although the number of cells did not decrease to the levels found in control non-sensitized animals, the decrease was dose proportional and highly significant (p < 0.002) when compared to OVA-sensitized mice which did not receive ASM-024.

A highly significant ( p = 0.002) association was estimated for residential BHTM contaminants among the 48 active smokers (RR = 1.11; 95% CI: 1.04, 1.18).

By contrast, gender was not significantly associated with Cluster 1, χ 2 (1) = 5.58, p = .02, and failed to reach significance for Cluster 3, χ 2 (1) = 9.41, p = .002.

These differences, however, proved highly significant ( P < 0.002) in the subset of children reporting a family history of obesity.

The amount of reduction in probing depth within the three groups was statistically highly significant (p=0.002**for group A; p<0.001**for group B and p<0.001** for group C).

>30 weeks post-infection from these 8 RM were highly significant (p = 0.002 for all samples, p = 0.0006 for BM by two-sided Wilcoxon Rank Sum tests).

There was a significant trend to having fewer patients in the advanced T-stage (p = 0.002) and N + groups (p = 0.01) within the perioperative chemotherapy group, despite randomization.

The Mann-Whitney test showed a highly significant relationship between age in years and the presence of zygomatic fracture (p = .002).

Proliferation was blocked in asthmatic IASMC by either the phosphoinositide 3 kinase inhibitor, LY294002 (3 μM), or a trend towards significance with the mitogen-activated protein kinase kinase (MEKK) inhibitor, PD98059 (10 μM) (p=0.002 and p=0.076, respectively, Friedman test, Dunn's correction) ( figure 3 B), which blunted extracellular regulated kinase (ERK) phosphorylation ( figure 3 C, D).

A highly significant increase in granulocyte count (GRA#) was observed among the exposed group with a p-value of p = 0.002.

There was also a significant trend to worse HRQoL represented by overall summary and physical dimensions scores with low TSAT ( P = 0.002 and P = 0.001, respectively), serum iron (both P = 0.03), and ferritin ( P = 0.03 and P = 0.02, respectively).

Anemia Among women, the trend over the 4 iron perception categories (none, a little, a medium amount, a lot) to anemia was highly significant ( P = 0.002).

The prolonged implant survival for the membrane-group is highly significant (p=0.002).

When all patients are considered, the decrease in serum calprotectin levels was highly significant over the 6-month period ( p = 0.002).

This difference was highly significant (not one of 500 random character deletion replicates had lower node recovery than the simulated fossilization aggregate, giving P = 0.002).

The survival data frequency distribution analysis, upon crossing the clusters by the overall survival results and the age groups, gave an extremely significant result in the mid-age population ( p = 0.002).

The secondary outcome of mortality was almost significant overall ( p = 0.07) and highly significant for people receiving supplemental oxygen at enrollment ( p = 0.002), suggesting a mortality benefit concentrated in this group.

Both current smoking rate and cessation rate remained to be highly significant even after controlling for age, education, occupation, and living apartment (p = 0.002 for current smoking rate and p = 0.004 for cessation rate).

In addition, we found that patients with high levels of C9orf86 expression showed a significant trend towards worse survival compared to patients with low C9orf86 expression (P = 0.002).

Interestingly, comparison between control tumors and shp16 methotrexate-treated tumors was highly significant both at day 30 ( P = 0.002) and at the timepoint when all shp16 mice had reach endpoint (day 55, P < 0.001), although we do note variability in this experiment ( Supplementary Fig.

In a later analysis of a smaller ( n = 356) subsection of the cohort with more complete data (18% missing LA Z-scores), the hazard ratio was lower, 1.03, and not statistically significant (whereas in contrast maximal wall thickness Z-scores hazard ratio 1.07 remained highly significant, p = 0.002).

The effect of DNMT3A genotype on birth weight and DNMT3B on length of gestation were the least significant before the exclusion and just below significance following the reduction in numbers; though the stronger DNMT3B effect on risk of prematurity remained highly significant (p = 0.002) after exclusion of the non-Caucasian pregnancies.

The health subscale was trending toward significance for patients with PHQ-9 > 10; these patients had higher transition readiness than those with lower depression screening scores (68.3 % v. 61.7 %; p = 0.002).

The predictor Threat (β = 0.278, p = 0.149) and familiarity (β = -0.287, p = 0.114) were not significant, however, the interaction term threat × familiarity was highly significant (β = -0.613, p = 0.002).