Excerpts

Logistic regression analysis showed that green tea consumption reduced the risk of aMCI in male participants (OR=0.657, P =0.019), and this finding was highly significant in males aged under 70 years (OR=0.376, P =0.002).

The success rate of block compared using Fisher's exact test was found to be highly significant in variation-3 ( P = 0.002).

When using a background of highly expressed genes instead of all genes, we observed a marginally significant enrichment for this GO term in “trans_enh” (4.7 fold enrichment, p < 0.002).

CNVR correlations Of the 110 CNVR evident in more than 2 individuals, 22 loci demonstrated a significant pairwise association ( p ≤ 0.05) with at least one other loci across all 7 breeds, 11 of which demonstrated highly significant correlations ( p ≤ 0.002).

In addition, among patients treated with adjuvant anthracycline-based therapy we found a highly significant association with OS both when included as a continuous (HR 4.19, 95% CI 1.67-10.51, P = 0.002) and as a dichotomized variable (HR 2.59, 95% CI 1.14-5.88, P = 0.02).

We detected a significant excess of variants in two of the pathways in CVID patients when compared to controls: Fc epsilon RI signaling and cytokine–cytokine receptor interaction pathways ( P < 0.001 and 0.002, respectively), plus two other marginally significant pathways after applying multiple test correction: cytosolic-DNA sensing, and NFKB signaling ( P = 0.002 and 0.001, respectively).

When considering the overall miRNA expression ( miRNA Sum ), the difference between healthy controls and ccRCC patients remained highly significant (U = 452.5, Z = −3.157, p = 0.002), confirming a distinct urinary miRNA signature associated with ccRCC ( Table 2 ).

Finally, the functional connectivity between (3) LMIFG → (2) LIFG showed a highly significant age effect ( r = 0.18, p = 0.002).

The association remained nominally significant in both Europeans (β=0.271; p=0.002) and African Americans (β=0.579; p=5.73 × 10–5) for the same risk allele.

The increase of natural external factors as perceived illness cause was highly significant, with mean S -value increasing from 4.40 ± 1.17 at first to 5.18 ± 1.52 at second measurement ( p = 0.002).

Splitting the analysis by gender consequently gave a highly significant association for women [χ 2 (1) = 10.71, p = 0.002] but not for men [χ 2 (1) = 0.052, p<1.00].

HADS-A score and anxiety rate at different time points HADS-A score was 6.9 ± 3.1, 7.3 ± 3.1, 7.7 ± 3.3, and 8.0 ± 3.5 at M0, M12, M24, and M36, respectively, which exhibited an increasing trend ( P = .002) (Table S1, Supplemental Digital Content, http://links.lww.com/MD/G520 ) (Fig. 1 A).

Furthermore, the plasma triglycerides-to-HDL ratio, a known marker for metabolic syndrome and highly atherogenic dyslipidemia,[ 18 ] showed a highly significant correlation with mFD (r = 0.480, p = 0.002).

The health subscale was trending toward significance for patients with PHQ-9 > 10; these patients had higher transition readiness than those with lower depression screening scores (68.3 % v. 61.7 %; p = 0.002).

Correlation analysis showed that among mice that reached the learning criterion in the cue discrimination task, there was a highly significant ( p = 0.002) correlation, when data from centromedial and centrolateral sites were combined, between learning index and the difference in area under the curve (AUC) of the dopamine responses to reward-predicting and non-reward-predicting cues (Fig. 5c ).

At lower than the median elevation capital, the relationship was highly significant ( P = 0.002).

They found 145 popliteal cysts in 382 knees (38%) and that there was extremely significant association between knee joint effusion and popliteal cyst ( P = 0.002).

Statistical analysis using only the highest lesional scores showed that there was a highly significant difference between endoscopic and histopathological PULS grading ( p = 0.002) (Table 3 ).

Using a fixed-effects model, the marginally significant reduction of the risk of post-ERCP abdominal pain associated with ulinastatin reached statistical significance (RR=0.71; 95% CI: 0.57–0.88; P=0.002; I 2 =67).

Remarkably, a support-vector machine-based multiparameter classificator built on these data achieved highly significant prediction performance with a balanced accuracy of 82.7% (Sens. = 76.5%, Spec. = 88.9%, p = 0.002, Fig. 1 a and Table 2 ).

In fact, reduced concentrations of IgA, IgG and IgM were seen in all MS patients who underwent apheresis ( n =6), with the decrease in IgG levels being highly significant (from 4.21 to 0.82 g/L or -81% on average, p =0.002).

The ammonia levels showed a decreasing trend over time ( P = 0.002).

In both hemispheres, we detected a highly significant association between inter-individual variations in the second topography and the behavioural battery (left hemisphere: ρ = 0.74, p < 0.002 (permutation test), Wilk’s Lambda = 0.0094, p < 0.005; right hemisphere: ρ = 0.73, p < 0.01, Wilk’s Lambda = 0.009, p < 0.002).

However, the quadratic model for TPC exhibited a highly significant lack‐of‐fit ( p = 0.002), indicating that the model did not adequately fit the experimental data (see Table S4 ).

In addition, a highly significant negative correlation was obtained between the urinary 8-OHdG levels and the serum oxidant capacity levels in C57BL/6J mice ( r = –0.6619, p = 0.002) (Fig. 4 ).