Excerpts

A smaller cluster in the symmetric region was marginally significant (Table 2 ). 3.4 Correlation analysis Significance for correlation analysis was determined as p < .0025 (0.05/20 for Bonferroni correction considering five clinical parameters and four stages) for each cluster.

Kaplan–Meier survival analysis demonstrated a near-significant ( p = 0.0530) association of PFS with HLA class I expression detected by the HC10 antibody and a highly significant association ( p = 0.0025) with HLA class II expression ( Figure 3 a,b).

This difference (0.062 mL on average) was statistically highly significant ( p = 0.0025).

In sharp contrast, CADA nearly completely blocked the upregulation of 4‐1BB in all samples (89 ± 4% and 79 ± 3% reduction in MFI for CD3/CD8 and PHA, respectively), which was highly significant (p = 0.0025 and 0.0011, respectively; paired t-test).

Statistical analysis revealed the following: channel diameter measurements gave highly significant difference when comparing white-blue (p = 0.0025), white-green (p = 0.0033), blue-red (p = 0.0001) and green-red (p = 0.0001) but no significant difference between white-red (p = 0.0586) and blue-green (p = 0.8017).

Subsequent statistical analysis (general linear model) revealed highly significant variations between trials for control lines of the circulating system ( p = 0.0025).

However, elevated expression of HER2 above 40.1 was highly significant for PFS (p=0.0025) and showed a trend towards significance for RFS (p=0.0587) (Figure 4 ).

The number of correct shifts for R-blocks 7 to 10 (28 out of 38) is highly significant (one-sided binomial test; p value = 0.0025).

The pooled data for side dishes 1 and 2 (consumption of salad 1, salad 2, or both) showed a highly significant association with disease (p=0.0025; [1.4<RR<∞]).

Highly significant differences in decidualization response were detected by measuring IGFBP-1 production at multiple time points after cAMP stimulation ( p = 0.0025 at 6 h; p = 0.0045 at 24 h; p = 0.0125 at 48 h).

To determine whether these highly significant microbiome signals ( P < 0.0025) could be used to distinguish children with ASD from their age-matched and sex-matched control counterparts, we trained random forest classifiers on train/validation/test splits of data derived from 16S-targeted sequencing and SMS–whole-genome sequencing of microbial communities.

It is worth to bring to mind that in a larger dataset of 34 teleostean species the correlation between MR and GCg was highly significant, p -value<2.5×10 −3 [24] .

Following the booster immunization, the HA6, fPE-HA6, and inactivated TX groups showed a highly significant increase in PBMC proliferation under SN stimulation compared to the PBS group (HA6 p = 0.0025, fPE-HA6 p = 0.0002, TX p < 0.0001).

In particular, the CC categories of 'cell', 'organelle' and 'protein complex' included 43.1%, 28.1% and 10.7% of Arabidopsis EST sequences against 52.6%, 34.6% and 5.3% of dicot cDNA-AFLP sequences, respectively (all pairwise comparisons in terms of absolute frequencies were significant or highly significant, being χ 2 ≥ 9.148 and P ≤ 0.0025).

Genomic alterations in FGF19 showed the strongest association with PFS with a borderline level of statistical significance of P = .00252 (Bonferroni‐adjusted significance level is .0025).

The average weight of the liver tumors and the weight of the total liver multiplied by the histologically estimated tumor fraction was 4.60 ± 1.11 for the control group and 0.49 ± 0.62 for the Ad-PRT-E group; this difference was highly significant ( p = 0.00254) (Fig. 6 D).

These alterations were highly significant: in ZNF441 -mutant ( p = 2.54 × 10 −3 ), in LAMB3 -mutant ( p = 5.16 × 10 −3 ), PNPLA6-mutant ( p = 3.00 × 10 −3 ), and in LNX1-mutant tumors ( p = 5.16 × 10 −3 ).

The two-sample t-test revealed that the difference between the averages was highly significant ( p -value = 0.002554). 3.2.

As mentioned in the previous section, the main effect of Confidence in performance was highly significant (F 3, 8.13 = 47.45, P = 0.0026).

weaker staining intensity) was also a highly significant (log-rank test; p = 0.0026) prognostic factor for cancer-specific survival rate.

No significant difference was detected between BHV-1 and PI-3, and between BAV-1 and BAV-3 antibody prevalence in sheep while extremely significant differences (p ≤ 0.0026) were observed between other viruses.

Conversely, the analysis revealed significant positive correlations with the STAI—T items: “I get in a state of tension or turmoil as I think over my recent concerns and interests” (rho(82) = 0.38, p = 0.0018) and a tendency toward significance with the item: “I feel like a failure” (rho(82) = 0.30, p = 0.0026).

At RAD54L , conditional analysis suggested that the common GWAS variants rs12142240 (reported by ReproGen) and rs12073998 (the strongest common-variant association we found, which is in high linkage disequilibrium with rs12142240) were in high linkage disequilibrium with all of the other genome-wide significant associations at the locus, and rare missense rs28363218 remained nominally significant at p = 2.6 × 10 −3 , suggesting its independence ( Table S9 ).

All P -values were two-tailed; P < 0.05 was considered nominally significant, and P < 0.0026 (Bonferroni correction P = 0.05/19) was considered a significant association.

The adjusted OR ( a OR) (99% CI) to complete ≥12 years of schooling stratified by parental SES, when comparing the childhood obesity cohort with the comparison group, showed a trend towards lower OR in the higher level of SES: low parental SES=0.69 (0.50 to 0.95), p=0.0026; medium-low parental SES=0.59 (0.48 to 0.72), p<0.0001; medium-high parental SES=0.46 (0.35 to 0.60), p<0.0001; high parental SES=0.27 (0.14 to 0.54), p<0.0001.