Excerpts

The difference of affected animals between the vaccinated and control group were highly significant ( p = 0.0026).

weaker staining intensity) was also a highly significant (log-rank test; p = 0.0026) prognostic factor for cancer-specific survival rate.

When considered together, SAE indvO and SAE indvN alleles showed a highly significant frequency decrease in HiP in relation to association strength (Z-transform tests; rank differences: combined P = 0.0026, correlations: combined P = 0.00021; Tests 2 and 3 in Table 2 ).

Using a sliding window of five consecutive SNPs, nominally significant haplotypic association (p = 0.0026) was identified in the region of PEPD at the SNPs rs10500265-rs6510383-rs7248389-rs7250833-rs2241380 (Table 3 ).

In spite of the small number of animals, the results were highly significant, p = 0.0026, based on Log-rank (Mantel-Cox) Test.

From that, we observed a significant trend (Cochran–Armitage test P value = 2.6 × 10 −3 ) whereby newly acquired genes appeared more frequent than ancestral genes in these regions ( Fig. 6A ).

The adjusted OR ( a OR) (99% CI) to complete ≥12 years of schooling stratified by parental SES, when comparing the childhood obesity cohort with the comparison group, showed a trend towards lower OR in the higher level of SES: low parental SES=0.69 (0.50 to 0.95), p=0.0026; medium-low parental SES=0.59 (0.48 to 0.72), p<0.0001; medium-high parental SES=0.46 (0.35 to 0.60), p<0.0001; high parental SES=0.27 (0.14 to 0.54), p<0.0001.

Both patients with high nuclear and cytoplasmic ADAR1 expression showed a trend toward shorter survival after distant metastasis (nucleus ( p = 0.0026) and cytoplasm ( p < 0.001); Fig. 1 C).

A plant-based diet was the most highly significant factor ( p = 0.0026) in ameliorating the risk of obesity in participants with a high genetic risk for obesity.

Using ANOVA, association of the three factors was highly significant (IL37 SNP (p = 0.0026); M2 (p = 0.0027); M6 (p = 0.0023)).

This reduction in HIV-1 particle release is highly significant ( n = 3 independent experiments, p value = 0.00265, Student’s t -test, and ANOVA statistical test for multiple comparisons indicate p value = 0.0089) since the gene editing of IRSp53 cannot be complete, nor edited by CRISPR/Cas9 knockout, without being toxic for the cells.

The increase from a mean of 28 ± 16 to 82 ± 20 was highly significant (p=0.00265, paired t-test).

Statistical tests revealed highly significant global differences among the different EEG rhythms in their capacity to characterize dementia pathology (Friedman test, χ 2 5 = 18.21 , p = 2.688 × 10 − 3 ).

Conversely, the repertoire of upregulated (Recurrent RD/No Recurrent RD ratio) and Recurrent RD-exclusive proteins revealed a highly significant functional signature pertaining to the pathologic conditions (PPI enrichment P -value = 0.00269).

The model indicated a significant increase in mutation frequency with age in blood, a marginally significant increase in saliva, and no difference in oocytes ( Z test P = 2.7 × 10 −3 , P = 5.7 × 10 −2 , and P = 0.688 for blood, saliva, and oocytes, respectively; Fig. 1B and table S4).

The effect of NDL was highly significant on influencing the error duration, which was found to be negative (i.e.,−8.9 ms; p -value = 0.0027).

Specifically, the nonlinear characteristics are highly significant for PM 10 (p=0.0027), SO 2 (p<0.001), CO (p<0.001), O 3 (p<0.001) and NO 2 (p=0.0460).

Both male and female mice showed a trend towards higher alpha-diversity with SCFA treatment, with male mice reaching statistical significance at the taxonomic levels of order ( p = 0.0027), class ( p = 0.0027) and phylum ( p = 0.043) and female mice reaching significance at the genus ( p = 0.049) taxonomic level ( Figures 2A,C , p -values for all taxonomic levels in Table 1 ).

A highly significant increase ( p = 0.0027, Welch’s two sample t -test) in the length of actin microfilaments was detected with a reduction in the cell thickness ( p = 0.0162, Welch’s two sample t -test) of MCF7 cells that induced K16 compared to control cells ( Figure 3 H,I).

FGFR4 expression, was detectable only in 6 of 81 patients (7.4%) and showed a highly significant correlation with a shorter OS (P = 0.0027). 3.3.

For subclonal mutations, all our observations remained significant (anti-EGFR, β = 9.86, P = 6.23 × 10 −05 ; DNA repair, β = 11.41, P = 2.94 × 10 −06 ; length of time on cytotoxic agents, β = 0.28, P = 0.0027), and there was a negative trend for the time between samples ( β = −0.15, P = 0.0027).

Moreover, an increasing trend toward liver steatosis severity was observed in patients with BMI ≥ 25 kg/m 2 (Cochran Armitage trend test = 3; p = 0.0027).

Among MS patients, highly significant deviations from HWE were seen for genotypes of DR~DQ haplotypes (p = 0.0027).

Although not all high ranked proteins occurred in both species, there is a highly significant correlation between the ranks of the 15 shared proteins (rho = 0.716, Spearman’s S = 159.3, p = 0.0027), suggesting some commonality in the importance of different processes.

Although no CPG showed significant enrichment after FDR adjustment, BRCA1 showed the highest frequency of P/LP carriers in NB patients (N = 7, 1.05%) and yield a nominally significant enrichment (Firth's logistic regression P = 2.7 × 10 −3 , OR = 18.76) as well as BRCA2 (N = 4, 0.060%, Firth's logistic regression P = 0.032, OR = 11.21) ( Fig. 2 b, Table 2 , Table S11 ).