Excerpts

Moreover, the frequency of positives from NAG to premalignant lesion and to intestinal-type GC showed a significant trend ( P =0.003).

Compared to our healthy cohort, the MWU indicated a highly significant difference for the CDT (FD −1.29 ± 1.37 vs. controls 0.038 ± 0.99; p = 0.003) and MPT (FD 1.51 ± 1.06 vs. controls 0.49 ± 0.94; p = 0.006) at the foot. 3.2.2.

Despite showing a trend in this direction, the difference between ∆P TM -based and PCWP-based diastolic stiffness constant β did not reach statistical significance (AUC difference, −0.081; 95% CI, −0.167 to 0.004; P = .003).

Association between HbA1c variability and renal function decline was significant in 53 patients with nephropathy (ACR≧30 mg/g) but did not reach statistical significance in 115 patients without nephropathy (r = -0.400, p = 0.003 and r = -0.169, p = 0.07, respectively).

Curvatures of hornets and honey bees leaving the hive followed a positive trend over the day (GAM, F = 9.263, p = .003 and F = 17.03, p < .001, respectively).

For false feedback, there was a highly significant effect of Lesion ( F 2,9 = 12.4, P = 0.003); pairwise comparisons between groups demonstrated that the amygdala-depleted groups were more likely to obey misleading feedback than controls ( F 1,6 = 26.1, P = 0.002) or OFC-depleted animals ( F 1,6 = 8.32, P = 0.028), while the OFC and control groups

Among the 663 patients with TNBC, pCR rates were 39.3% with bevacizumab vs 27.9% in controls, and the difference was highly significant (odds ratio [OR] 1.67, 95% CI 1.21–2.31, P =0.003).

In the subgroup with COPD, the younger group took longer to return to their baseline COPD condition than the older age group ( P =0.004), as did hospitalized participants compared to nonhospitalized participants ( P =0.025), although these differences did not reach statistical significance when adjusted for multiplicity ( P <0.003).

Although the results did not survive Bonferroni correction, nominally significant enrichments were observed for platelet sensitization by low-density lipoprotein cholesterol ( p = 0.003), IL-7 signaling ( p = 0.004), glycerophospholipid biosynthesis ( p = 0.005), and viral messenger RNA synthesis ( p = 0.011) ( Figure 2 and Supplementary Table 5 ).

Average Triglyceride in the first, fourth and seventh phases were 128.57 ± 13.33, 101.43 ± 57.99 and 87.40 ± 57.59 mg/dl, respectively, which shows a decreasing trend (P = 0.003).

There was a highly significant correlation between plasma PGRN and IL-6 levels in patients with FTLD, overall ( r = 0.195, p = 0.003), but not so in AD, or control subjects.

However, there was a highly significant three-way interaction between the factors ‘condition x column x optic radiation integrity’ (F(9, 207) = 2.847, p = .003).

This difference in the enhancer was highly significant as assessed both by a Mann–Whitney test ( p = 0.003) and by a permutation test (200 permutations, p < 0.005).

A highly significant difference ( P = .003) was observed in the mean packed red blood cell units transfused between the fixation and replacement (0.93 and 1.87, respectively).

On multivariate analysis, a lower PNI (< 44.91) and worse response rate (SD + PD) showed a trend toward reduce PFS (P = 0.003 and P < 0.001).

Data showed also a nonsignificant trend toward greater protective effect in studies using a dual-ring protector (RR = 0.31, 95% CI 0.14–0.67, P = 0.003), rather than a single-ring protector (RR = 0.83, 95% CI 0.38–1.83, P = 0.64).

Importantly, there was a highly significant correlation between HIV-1 CA-RNA transcription in CSF cells and HIV-1 CA-RNA transcription in CD4+ T cells from PBMCs ( Fig. 1 H ; r = 0.83; P = 0.003).

In particular, 44.3% of psoriasis patients showed TMJs versus 22.3% of controls ( p value<0.001): clicking was recorded in 33% of the psoriasis group (with and without PsA) and 15.2% of controls, with a highly significant difference ( p value=0.003) and crepitation in 11.3% of psoriasis patients and in 7.1% of controls ( p value>0.05).

Although all patients in the MC group presented with GMG compared to 70.3% in the non-MC group, this difference did not reach statistical significance after adjustment ( p = 0.003; P -adjust = 0.062).

Finally, Model 4, which additionally incorporated ApoA1, ApoE, and Lp(a), confirmed log10UcyC as a highly significant predictor (OR = 1617.907; 95% CI: 12.973–201769.226; p = 0.003).

A Kruskal–Wallis test revealed this difference to be highly significant ( p < 0.003).

Renal Function Tests The results showed a highly significant increase in creatinine levels in the infected + MTZ-treated group compared to the non-infected non-treated group ( p = 0.003).

However, it can also be noted that the difference in phenotypes were highly significant ( p = 0.003 and p < 0.0001 for the WB and FE phenotypes, respectively), suggesting that the relative differences in global expression patterns could be considered representative of a larger phenotype population.

The overall difference between malignant and non-malignant tissues was highly significant (MethIndex was mean ± SD = 44 ± 20% in HCC versus 24 ± 20% in NT, p = 0.003, Figure 2 C).

A test for linear trend was highly significant, p = 0.003.