Excerpts

A CV-ANOVA test showed highly significant variation related to the separation of groups: for plasma data: p -value = 0.005; for interstitial fluid data: p -value = 0.003; and for urine data: p -value = 0.003.

The permutation test analysis showed ( Figure 3 A) that the OPLS-DA model had a goodness-of-fit R 2 Y value of 0.950 and a predictability Q 2 value of 0.727 after 200 random simulations, both of which were highly significant levels ( p < 0.005).

Results Interrelations between simulated incisor protrusion and the resulting soft-tissue changes were statistically highly significant ( p < 0.005) and nearly linear.

Magnesium showed a borderline significant association with NLR that remained significant after FDR correction ( p = 0.005, q = 0.009); however, its associations with SII and MLR did not survive correction.

Figure 4 shows that the expression of AMP deaminase and myogenic 6 is quite significant ( p-value < 0.005) as noted by asterisks in the HB group and insignificant in other groups.

This difference was highly significant (P = 0.005).

Correlation of FtsH expression with the generation time of the AOB cultures was highly significant (Spearman’s correlation = -0.85, p < 0.005, n = 9).

The total indirect effect was highly significant ( β = 0.106, P = 0.005).

Median chitotriosidase values showed highly significant commensurate reduction with eliglustat treatment in both cohorts ( P ≤ .005): 24% in non‐splenectomized switch patients and 38% in splenectomized switch patients after 2 years in this real‐world cohort compared to 63% after 4 years in ENCORE. 20 The safety of daily oral eliglustat cannot be assessed in the Registry, because adverse event data and reasons for discontinuing treatment are not captured.

There was also evidence for a highly significant interaction between birthweight (dichotomized around 2500 g) and age that predicted variation in epigenetic age acceleration ( b = −0.39, p = 0.005).

All biomarkers demonstrated highly significant relationships with both CDR status (all P < 5 × 10−3) and continuous MMSE score (all P < 5 × 10−6).

By simulating all possible combinations of scores across the 5 (penetrations) × 16 (electrode contacts) recording grid and assuming the null hypothesis that any differences arise by chance, we found that a score of ≥2, or ≤−2, could be considered significant at p < 0.005.

In GAM_02, which included a temporal variable “year” in addition to the environmental predictors, humidity, vegetation index and the temporal predictor were statistically significant predictors ( P <.005), while the effect of wind speed was weakly significant in this model ( P >.005).

The quantitative analysis showed the trend of total anthocyanin content ( Figure 2A ) being consistent with previous optical measurement ( Figure 1B ), and only the C2-vs-C3 comparison was extremely significant (p=0.005) for adjacent stages.

Since the mechanical studies in STAT3-OKO-M mice all yielded highly significant effects (p<0.005), while the studies in STAT3-OKO-BL, despite similar effect sizes, did not achieve the 0.025 threshold, we sought to further confirm our prediction of defects in intrinsic parameters consistent with altered bone quality by determining whether meta-analysis of the combined studies yielded significant effects.

A significantly increased rate of postoperative complications was apparent in this most recent cohort of patients who were smokers at the time of surgery, and the difference in terms of the rate of overall complications was statistically highly significant (p < 0.005).

Among 40 genes enriched in our cohort, four genes were found with trend toward significance: POLR3A ( p = 0.005), SUFU ( p = 0.006), LHX3 ( p = 0.021), CREB3L4 ( p = 0.040) ( Tables 3 and S2 ).

Data have been considered statistically significant with a p -value <0.05 (asterisk) and highly significant with p -value <0.005 (two asterisks) [ 28 ]. 4.8.

There was also a marked improvement in the subscale Daytime Dysfunction in the whole sample, where the main effect of Session was highly significant ( F (1, 30) = 9.19, P = 0.005).

Linear polynomial contrast analysis showed a significant trend for IQ over the three groups (p = .005), with lowest IQs in SGA- children.

The age, smoking, as well as the levels of BMI, AHI, ODI, MAT, TSA90 and the prevalence of hypertension and COPD exhibited a decreasing trend with the elevated MSpO 2 , except for the levels of LSpO 2 and the prevalence of dyslipidemia, which showed an increasing trend (all P < 0.005).

Glass slides inoculated with MRSA strain M1 and treated with singular phage showed highly significant reductions in CFUs (p ≤ 0.005) compared to mock treatments ( Fig 2B ).

These covariates were all highly significant (p<0.005), and accounted for 38.9% of variability in log e mean CIMT.

In this analysis, rs875725 in intron 33 had the strongest independent effect ( P = 6.4 × 10 −05 ), with three other SNPs in the 3′-region having moderately significant ( P < 0.005) associations.

Our data support that greenstick fracture is a highly significant risk factor for the occurrence of refractures in DMRFs with an OR of 3.4 ( p = 0.005).