Excerpts

Median chitotriosidase values showed highly significant commensurate reduction with eliglustat treatment in both cohorts ( P ≤ .005): 24% in non‐splenectomized switch patients and 38% in splenectomized switch patients after 2 years in this real‐world cohort compared to 63% after 4 years in ENCORE. 20 The safety of daily oral eliglustat cannot be assessed in the Registry, because adverse event data and reasons for discontinuing treatment are not captured.

The difference is highly significant between the emm pattern A-C and E strain groups ( p < 0.005), but not significant when pattern D and E strains are compared.

There was a trend towards significance with MS-impact (MSIS-29; rho = −0.19, p = 0.005), physical fatigue (MFIS physical; rho = −0.19, p = 0.006) and anxiety (HADS-A; rho = −0.21, p = 0.003).

1 , Pearson’s correlation test yielded highly significant correlation (r 2 =0.6808, P <0.005) between the CAM and mice treated with IV drugs ( Fig. 1A ).

In the ICAN data, Spearman correlational analyses between age and TBR for all permutations showed highly significant correlations (all Cz p < 0.005 unless stated otherwise), as expected, with the strongest correlations for the Session-based averaging method ( r = − 0.28; df = 234) followed by Welch (Hann) ( r = − 0.27; df = 234) and the weakest correlation for Trial based ( r = − 0.26; df = 234).

The test compares each method’s performance against a theoretical median of zero, with all approaches yielding highly significant p-values of 0.002 ( p < 0.005), confirming substantial improvements over baseline performance.

nebulosum , is excluded this difference is highly significant ( t = 3.583, d.f. = 6.354, p = 0.005).

In addition, we detected highly significant monocyte enrichment (p ≤ 0.005) after magnetic isolation ( Fig 2F ) when compared to the protocol following step (a) only (89.0 ± 5.1% vs. 22.7 ± 8.6%) ( Fig 2E and 2F ).

In both situations, the differences are markedly significant (obesity p < 0.005 and gender p = 0.062).

A highly significant ( p = 0.005) negative correlation was found between ampicillin and both tetracycline (r = −0.375) and oxytetracycline (r = −0.376) detection using HPLC.

Pearson's correlation test was used, and a highly significant result was found between BMI and PPD ( P ≤ 0.005), whereas others were nonsignificant.

There was also a marked improvement in the subscale Daytime Dysfunction in the whole sample, where the main effect of Session was highly significant ( F (1, 30) = 9.19, P = 0.005).

However, no statistically significant differences were found among RNL, SF and SF-OCT samples in the tested genes, except for Jun gene expression, being slightly significant lower on SF compared to SF-OCT samples (p<0.005).

P -values for non-progression as measured by ES were highly significant ( p < 0.005), indicating a slowing down in joint erosion during ETN treatment.

Analyzing the trend in the different age groups there was a highly significant statistical difference (p < 0.005).

Highly significant Ki67 decreases occurred in all tumour subgroups at 10–14 days ( P <0.005).

Magnesium showed a borderline significant association with NLR that remained significant after FDR correction ( p = 0.005, q = 0.009); however, its associations with SII and MLR did not survive correction.

This difference in % inhibition of thymidine uptakes between two groups was highly significant ( P <0.005) ( Figure 1b ).

In support of this, various correlations exist between the shape of individual squamate brain subdivisions and locomotor modes, with the cerebellum and diencephalon exhibiting the most highly significant values ( P values < 0.005; table S3).

A statistically significant difference was considered at the level of p < 0.05, *** highly significant ( p < 0.0005), ** moderately significant ( p < 0.005), * significant ( p < 0.05). 2.8.

Decreasing odds ratios (ORs) were discovered for increasing AMED scores, with a significant trend in risk ( p = 0.005).

The prevalence of methicillin resistance showed a decreasing trend ( P = 0.005) (See Supplementary Fig. 1, Additional File 1 ).

The linear regression of PS101 dose on overall survival indicated a slope of 1.46 days/ml/kg of PS101 with a highly significant correlation (95% CI = 0.90 to 2.02, R 2 = 0.90, p = 0.005) in addition to the 34 days of survival when treated with irinotecan alone ( Figure 5A ).

Highly significant differences were demonstrated between single activity levels (A-D: P < .005; E-H: P <.0001). 3.2.5 Psychometrics Median HADS-A scores were 6.0 (5.0–7.0).

In particular, when compared to physiological range, the autonomous sitting acquisition was delayed in 63.2% of the patients, with a significant trend in male patients ( p = 0.005).