Barely Significant

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an increasing trendp < 0.0050.1× alphagold
Precipitation showed an increasing trend for the whole Yunnan except for ecoregion IV from 1982 to 2008, with a significant increase in precipitation in ecoregions I ( p < 0.005, R 2 = 0.25) and II ( p < 0.005, R 2 = 0.16), a weak increase in ecoregions III ( p = 0.12, R 2 = 0.08) and V ( p = 0.11, R 2 = 0.08), and a slight decrease in ecoregion IV ( p = 0.36, R 2 = 0.01) ( Figure 4 ).
highly significantp = 0.0050.1× alphaqualifiedgold
There was no statistically significant difference in disease duration since the introduction of the first csDMARD or bDMARD treatment, but the duration of disease at the introduction of the current bDMARD treatment was significantly shorter in the reduced-dose group than in the stable-dose group (9.7 vs 12.1 years, p = 0.034) (Table 1 ). In addition, we noted that there were proportionately more patients treated concurrently with MTX in the reduced-dose group than in the stable-dose group, and the difference was highly significant (86.7% vs 73.8%, p = 0.005).
highly significantP = 0.0050.1× alphaqualifiedgold
The result is plotted in Figure 4 , illustrating the finding that HERVK PBA increases significantly with age (r = 0.357, P = 0.002) (It can be seen in Figure 4 that there is a high PBA value; if that is removed from the analysis, the positive association between and HERVK PBA remains strong and highly significant [r = 0.326, P = 0.005], attesting to the robustness of this effect). 3.4 HLA alleles in the very old and their association with virus PBA We then analyzed the PBAs of the 13 viruses in 11/13 VOA alleles (alleles C*02:02 and C*03:02 could not be modeled by the IEDB NetMHCpan affinity tool) using a repeated-measures analysis of variance (ANOVA), where virus PBAs were the dependent variables.
highly significantp < 0.0050.1× alphaqualifiedgold
In the ICAN data, Spearman correlational analyses between age and TBR for all permutations showed highly significant correlations (all Cz p < 0.005 unless stated otherwise), as expected, with the strongest correlations for the Session-based averaging method ( r = − 0.28; df = 234) followed by Welch (Hann) ( r = − 0.27; df = 234) and the weakest correlation for Trial based ( r = − 0.26; df = 234).
highly significantp = 0.0050.1× alphaqualifiedgold
The analogous analysis for mortality identified RSV as highly significant risk factor (p = 0.005; OR = 4.4), besides age (p = 0.011), sex (p = 0.007), oxygen upon admission (p < 0.001), cough (p = 0.031) and eGFR (p = 0.045), while Influenza A was not (p = 0.861).
At 6 months, the proportion of participants achieving UPCR ≤0.5 g/g was numerically greater in the voclosporin arm compared to the IVC arm, although the difference did not reach statistical significance; the proportion of participants achieving UPCR ≤0.5 g/g was significantly greater in the voclosporin arm compared to the MMF arm (p<0.005).
Although individual differences generally failed to reach statistical significance for genes other than R10 (Table 2 ), these distributions of differences for LGR and LP (χ 2 = 8.0, P = 0.005) as well as for SD (χ 2 = 2.0, P = 0.10), are unlikely to be due to chance only.