Principal findings Immunization of outbred mice with MAP-2 in combination with alum and/or MAP-1 elicited highly significant ( P < 0.005) reduction of around 60% in challenge S . mansoni worm burden and no increase in worm eggs’ loads or vitality, compared to unimmunized or alum pre-treated control mice.
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2.0%, p = 0.013), and the rate of acute renal failure showed an increasing trend as BMI increased ( p = 0.005).
Since the measurements on samples with added VLDL or LDL showed an increased level of the particles measured in each subgroup after addition, it is highly significant for most of the subgroups: for each subgroup, p < 0.005, n = 8 ( Table 1 ).
In addition, we examined which associations presented a highly significant effect at p<0.005, absence of large or very large between-study heterogeneity ( i.e.
Removing outlying values from this model also, the difference between bitches housed individually and those maintained within a group remained statistically significant ( Table 3 F); however, only in grouped bitches was there a decreasing trend of the probability of pregnancy failure with the increasing number of bitches (Solution for fixed effects, slope = −0.25, t = −2.86, P = 0.005).
Corresponding Mann-Whitney U tests were highly significant (all p < 0.005), and these associations withstood adjustment for multiple testing.
An analysis of variance revealed a statistically highly significant difference ( P < 0.005) among the different posts used, and a statistically significant difference between carbon posts vs. zirconia posts, carbon posts vs. everStick posts, and zirconia posts vs. everStick posts ( P < 0.05).
The connectograms display highly significant Pearson correlations ( p < 0.005), with p-values corrected for multiple comparisons using the false discovery rate (FDR) method.
In this context, the mScarlet-based biosensor showed minimal response (0.3 ± 0.2%, n = 11), whereas the stagRFP counterpart showed a clearly significant FRET response (3.3 ± 0.4%, n = 8, p = 0.005, t = 3.642, df = 9) (Fig. 3a ).
Nevertheless, a significant trend was observed towards a reduction in the incidence of flap necrosis in the context of breast reconstruction (OR = 0.61; 95% CI: 0.44 to 0.86, P = 0.005, I 2=0%).
Differences were considered as 'not significant' with P values > 0.1, 'tendentially significant' (significant*) with P values between 0.1 and 0.05, 'significant' (significant**) with P values between 0.05 and 0.005, and 'highly significant' (significant***) with P values < 0.005.
The results of this model show no significant effect (p = 0.18; statistical power [95% CI] = 42.60% [39.51, 45.73]) of the rank on perseveration but there was a highly significant effect (p = 0.005) of centrality on perseveration, the most central individuals made less perseverative errors ( Fig 3 ).
In contrast, BA19 manifested a relatively sustained correlation with RT in its alpha modulation, which was highly significant from the middle (530–950 ms; p < 0.005) of the actor's pointing movement until participants made their response (1410 ms).
Although a decreasing trend with age was observed, the overall difference among groups was statistically significant ( p = 0.005).
Improved mean BOP, PPD, and CAL differences were highly significant ( P < 0.005) for the test group at the 6 th week.
In addition, both overall survival and leukemia-free survival rates showed a favorable trend toward the CAR T-cell+SCT group, respectively (hazard ratio, 0.44; 95% CI, 0.25–0.77; P =0.005; I 2 =0%; evidence, low; and hazard ratio, 0.29; 95% CI, 0.17–0.49; P <0.00001; I 2 =0%; evidence, low).
Relationships to latitude (all species; or with species grouped by PFT) were quantified with ordinary least squares (OLS) regressions – including a quadratic term, as this clearly improved the fit to data and the quadratic term was in all cases highly significant (all P ≤ 0.005).
Two-way ANOVA revealed that the impact of the three independent factors (the total volume of solvents, the concentration of Mg stearate, and the ambient temperature during stirring) separately was highly significant ( P < 0.005) on the %EE.
Further comparisons demonstrated that CSEO was significantly more effective than the reference group in modulating oxidative stress parameters (* p < 0.05), with highly significant differences noted for certain markers (*** # p < 0.005).
In contrast, the EV-MP group demonstrated a robust upregulation around 20-fold for CD163 and around 7-fold for CCL18, which were highly significant ( p < 0.005) compared to both MP and F-MP groups.
At 6 months, the proportion of participants achieving UPCR ≤0.5 g/g was numerically greater in the voclosporin arm compared to the IVC arm, although the difference did not reach statistical significance; the proportion of participants achieving UPCR ≤0.5 g/g was significantly greater in the voclosporin arm compared to the MMF arm (p<0.005).
Highly significant differences were defined in cases with p -values ≤ 0.005 and significantly different cases with p -values between 0.05 and 0.0051. 5.
There was a marginally significant effect for Target, F (1, 49) = 12, p < 0.005, with Love (0.457) less than Salted (0.468).
Specifically, the comparison with the SPEA method shows extremely significant differences on the COBRE, Nottingham, and Xiangya datasets ( p < 0.005), and the comparison with PSO-MET has p values less than 0.025 on all datasets, indicating that the differences are highly statistically significant.
The reduction in the number of surviving cells at 4μM, 20μM and 100μM of WDL ( Figure 1 ); at 1.60 μM, 8μM, 40 μM and 200 μM of BA ( Figure 2 ) while at 12μM and 60μM of EGCG ( Figure 3 ) was highly significant than respective controls (***P < 0.005).