The overall multivariate log-rank test was highly significant (chi-squared = 71.16, p < 0.0001), confirming significant differences in conversion-free survival across dose groups.
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For example, the WTCCC [13] required a marginally significant (p-value<10 −4 ) GWAS SNP to support the evidence at a genome-wide significant imputed SNP.
M+F+A− genes were also significantly overrepresented on the X at a 2-fold expression threshold ( f (X) = 0.26, p = 0.03), and at larger thresholds the effect became highly significant, the frequency of X-linkage reaching 0.50 ( p = 0.0001) and 0.57 ( p = 0.0002) for 5- and 10-fold overexpressed genes, respectively.
The difference between p35S : cOBE3 wus-1/+ and empty vector wus-1/+ control is highly significant in both seedling and shoot stages (both Chi square, p<0.0001).
Differences between the 5′ regulatory and 3′ coding regions were highly significant ( p < 0.0001).
Median emPHasis-10 scores were 3, 19, 31 and 40 in WHO functional classes I, II, III and IV, respectively, with highly significant differences between the scores in each functional class (all p<0.0001).
The quantification of the removal of immunogenic material in 4 cm- and 8 cm-long segments also showed a highly significant (adjusted p -values < 0.0001) removal of immunogenic material.
ANOVA analysis in T-47D cells though showed significant but only MBD1 & MBD2 genes have highly significant P <0.0001 change in protein expression concerning resveratrol.
The Kruskal–Wallis test indicated a highly significant difference in plasma PlGF concentrations (P < 0.0001; Figure 2 ) between groups.
For cases involving a central DSB node (Experimental Section), we observed an increasing trend in DSB probability from the single‐pattern to the multiple‐pattern category (p < 0.0001, Proportion test, Figure 4B ).
Statistical analysis using one-way ANOVA confirmed that the differences in biofilm formation between treated and untreated groups were highly significant ( p < 0.0001 for Δ agrA and MRSA).
The overall differences were highly significant: Wilks’ Lambda: 0.02 ~ F 168,1549 = 7.26 P < 0.0001, and the squared Mahalanobis distances provided the specific P -values between groups ( Table 2 ).
The average response to shifting between gluconate and Cl − -Ringer's was a highly significant reduction of the pH-gradient from 1.08 ± 0.07 ( n = 199) to 0.59 ± 0.09 ( n = 134) pH-U/500 μm ( P < 0.0001, N = 43) The range of pH-gradients in Cl − -Ringer's was 0.06–2.57 pH-U.
Pathologic complete response was a highly significant predictor of DFS and OS in all treatment groups (HR = 0.45, P < 0.0001, and HR = 0.33, P < 0.0001, respectively).
The test for residual heterogeneity was highly significant ( p < 0.0001). 4.4.1.2 DBS primary for treating chronic pain (DBS-P) analysis The test of moderators for age as a predictor was not significant F(df1 = 1, df2 = 22) = 1.1608, ( p = 0.29), indicating that age did not significantly moderate the effectiveness of DBS-P for chronic pain The estimated amount of residual heterogeneity (tau^2) was 43.86, indicating considerable heterogeneity among the studies.
Regional comparison (Paired t-test) In contrast, a highly significant difference was observed between the maxillary and mandibular vertical components within the same specimens ( p < 0.0001).
The amount of activated microglia (RPT) was decreased in a highly significant manner, from 57.47% to 32.50% (**** P ≤ .0001), after 24-hour incubation at a concentration of 25 μg/mL TPM and to 43.17% (n = 18; ** P < .01) at a concentration of 50 μg/mL TPM.
Figure 2B illustrates the comparison of true versus predicted ages, yielding a Pearson correlation coefficient r of 0.56 and a highly significant p -value ( p < 0.0001).
ANOVA showed that both season (i.e., autumn and spring) and population had a highly significant effect on mass-specific energy content of lipid and glycogen stores ( P << 0.0001; Table S2 ).
The multiple regression model was highly significant [ F ( F (2, 114) = 117.9, p < 0.0001] and the R squared was equal to 0.67.
This test indicated a highly significant difference among cell types (χ 2 (8) = 276.98, p < 0.0001).
Both these associations were highly significant (p-value<0.0001).
However, that for the ‘Fiction’ condition is highly significant (r 2 = 0.388; F 1,39 = 24.75, p < 0.0001).
For both chromosome I and X , there was an extremely significant increase in the number of painted chromosomal segments between pre-meiotic nuclei and TZ-NF nuclei (p<0.0001), reflecting a substantial elongation of chromosome territories following meiotic entry.
Conversely, as found for bottlenose dolphins ( Williams et al., 2017b ), there were highly significant relationships between V̇ O 2 ss (J kg −1 min −1 ) and f S (strokes min −1 ) ( n =30 swims, d.f.=1, 28, F =25.53, P <0.0001, AICc=304.28, BIC=308.29; Fig. 4A ) for beluga whales, where: (1) and between V̇ O 2 ss (J kg −1 min −1 ) and swim speed ( U swim , m s −1 ) ( n= 30 swims, d.f.=1, 28, F =54.93, P <0.0001, AICc=288.48, BIC=291.76; Fig. 4B ), where: (2) even within the relatively narrow range of exercise efforts representing the preferred performance levels of the individual whales.