Excerpts

The results remained highly significant (p=0.0002).

However, during reversal phase, the analysis of trials to criterion revealed a highly significant effect of WD in both 7 and 16 months old mice (Two-way ANOVA p = 0.0002, Bonferroni post tests * p < 0.05; Figure 1D ).

Cox regression with clustering on pedigree showed that the exon was a highly significant predictor (χ 2 19.75 with 3 degrees of freedom, p = 0.0002).

Interaction terms X1X2 ( p = 0.0285) and X2X3 ( p = 0.0202) were moderately significant, with X2 2 showing a non-linear impact ( p = 0.0002).

At the lower dose of sucrose and higher dose of OLE, a highly significant decrease ( p < 0.0002) in peak glucose was observed in all individuals (Fig. 8 ).

The CCDR Score demonstrated moderate negative correlations with VSMT (r = −0.347, p = 0.008) and GFC_VSMT (r = −0.368, p = 0.005), as well as stronger negative correlations with GFC_CCDR (Regression) (r = −0.628), GFC_CCDR (Discriminant) (r = −0.504), and the GFC_Health Problems Score (r = −0.471), all of which were highly significant ( p < 0.0002).

8 ), and this difference was highly significant ( N =16; t=4.87; P =0.0002).

This would be highly significant statistically ( p = 0.0002), but Steinmann’s description was limited to a schema, without narrative details, and Schwingenheuer’s was also brief.

The gender difference is highly significant (t(62) = 3.83, p < 0.0002, two-tailed, with an effect size Cohen’s d = 1.025).

he difference between the experimental and control conditions was highly significant (paired t (4) = 13.50, p = 0.0002, Cohen’s d = 9.55).

In the female subsample, the effects of DDSS and age were both highly significant (Q = 14.7; p = 0.0002, Q = 23.8; p < 0.0001, respectively), but the effect of DDSS on usability ratings was different for younger patients than it was for older participants (Q = 7.9; p = 0.005), suggesting that younger women (<52 years) showed greater usability rating differences between Ada and Rheport.

A highly significant negative correlation was seen between Mig-6 and FPG (r=−0.4991, p=0.0002), HbA1C (r=−0.4649, p=0.0008), and HOMA-IR (r=−0.4272, p=0.0027) ( figure 3 A).

Highly significant association was seen between breast cancer and carrying either of the mutations (OR 1.86, 95% CI 1.32–2.49, P = 0.0002).

As expected, a highly significant correlation was observed between the number of Gag escape mutants associated with the protective HLA alleles and decreasing VRC (r = -0.33, p = 0.0002, Fig 4A ).

coli O157:H7 was extremely significant compared to the control ( p = 0.0002), but ratios of Fura-2 with non-target bacteria weren’t found the significant differences compared to the control ( p > 0.05) in the ground beef extract samples.

Between visit spectral changes were highly significant ( p = 0.0002) and were related to protein structure.

This meta-analysis failed to show any benefits of adjuvant bisphosphonates in premenopausal women, but highly significant improvements in bone recurrence (RR = 0.72; 95% CI 0.60–0.86, 2 p = 0.0002) and breast cancer mortality (RR = 0.82; 95% CI 0.73–0.93, 2 p = 0.002) were seen in the 11,767 postmenopausal women included in the meta-analysis.

For confirmation, we applied IFNA16 rs28368163 as a tag SNV in a second ET validation cohort (n = 54) and reconfirmed a highly significant association ( P = .0002) and OR (4.51; CI, 1.92-10.56), nearly identical to that found in Cohort 1 ( Table 2 ).

1b ) revealed highly significant correlations of PC1 and PC2 with hepatic zones (PC1: r = 0.47, p = 2.0 × 10 −4 ; PC2: r = 0.86, p < 2.2 × 10 −16 , Supplementary Figure 3) indicating zonation as a major driver of variation between samples.

Two weeks after surgery (visit 2), TBUT showed a trend toward the initial mean value observed at the screening visit in group A, while it further decreased in group B ( p = 0.0002).

The Ctn reference ranges determined in this way for patients with nodular thyroid findings (90% confidence intervals) were <3.0 to 9.1 pg/mL for women and <3.0 to 14.1 pg/mL for men, i.e., very similar to the reference ranges specified by the manufacturer and with a highly significant sex difference ( p < 0.0002).

Further analysis of the number of Filament Terminal Points revealed highly significant differences between the following time points: DIV1 and DIV7 ( p = 0.0002), DIV1 and DIV10 ( p = 0.0071), DIV3 and DIV7 ( p = 0.0002), DIV3 and DIV10 ( p = 0.0062), DIV5 and DIV7 ( p = 0.0005), and finally DIV5 and DIV10 ( p = 0.0157) (Fig. 4h ).

The correlation between the number of BS and gene transcription levels was markedly significant (Supplementary Fig. 10c , p = 0.0002; Pearson correlation analysis).

The time domain features showed a highly significant distinction ( p -value = 0.0002), indicating a clear dissimilarity between the AD and baseline groups in this domain.

However BSO has a highly significant (p = 0.0002) effect in these cells when used in combination with 8 μM ATO.