Excerpts

The results shown in Figure 3 , demonstrate a highly significant improvement in the survival time in Aldoxo-treated mice as compared with control or Doxo-treated mice ( P = 0.0002 for each comparison).

Results Metabolism of MMST Fasting total serum silicon For the 14 participants with complete serum datasets, four weeks of supplementation with MMST led to a markedly significant increase in fasting serum silicon concentration (mean 272 μg/L) compared to baseline (mean 173 μg/L: P = 0.0002) or to placebo (mean 191 μg/L: P = 0.003) (Figure 2 A).

cereus HKS 1–1 was highly significant ( p < .0002) among the test strains. 3.2.2 Antibiotic sensitivity test The strains of B. cereus were found susceptible to different antibiotics (Table 2 ) in the Epsilometer test (E‐test) method, which was referred as an authentic way of high‐throughput sensitivity detection by Turnbull et al.

To reduce the bias of time to HSCT2 we analyzed only patients having HSCT2 within 6 months of relapse and found that having HSCT2 was a highly significant predictive factor in this univariate analysis ( P =0.0002).

A highly significant correlation was obtained for tumor volume measurements (Pearson correlation coefficient r = 0.90, CI: 0.654 – 0.974, p = 0.0002) using micro-CT-scan examination when compared to autopsy findings (Fig. 4b ).

This analysis revealed highly significant dependencies between FAA and the six EDA features (all p < 0.0002 ), indicating robust non-linear relationships.

The differences between the populations are highly significant for both Cmax values, as determined by 3-group permutation ANOVA (p < 0.0002 for both) and pairwise Wilcoxon test for sparse vs dense (p = 2e-18 and p = 9e-14 for Cmax = 90 nM and 900 nM, respectively).

The difference was highly significant (P = 0.0002).

Ureteroscopic laser lithotripsy achieved a highly significant stone-free rate ( p = 0.0002), and the mean operative time, auxiliary procedures, and postoperative complication rates were comparable between the two groups.

Cytotoxic effects of 5′DFUR, and to a lesser extent those of 5FU, were enhanced in TP clones as compared to control cells: there was a highly significant correlation between TP activity and in vitro sensitivity to 5’DFUR (r 2 = 0.91, P = 0.0002, n = 8) and, to a lesser extent, to 5FU (r 2 = 0.49, P = 0.053, n = 8).

This was a highly significant difference ( p = 0.0002).

WGCNA highlighted a highly significant “turquoise” module comprising 78 downregulated genes ( P = 2e − 04).

However, there was a highly significant decline in the amplitude of the AHP in all cells by 13.5 + 3.2% ( n = 12, P = 0.0002) ( Fig. 7 A and D ).

Two weeks after surgery (visit 2), TBUT showed a trend toward the initial mean value observed at the screening visit in group A, while it further decreased in group B ( p = 0.0002).

This increase starts already at birth, remains constant throughout childhood s as shown by other groups ( 4 , 9 ) results in relative increase of the memorand adolescence, and is highly significant (linear regression intercept p = 0.0002, slope p = 0.54) (Figure 1 C). cTFHs Are Expanded in DiGeorge Syndrome To correct for the relative increase of memory CD4 + T cells in DiGeorge, we compared the percentages of CXCR5 + memory CD4 + T cells (cTFHs) of all memory CD4 + T cells (gating strategy shown in Figure 2 A).

As shown in Figure 4C , the differences approached significance in the case of isoform B (t = −1.97, p = 0.059) and were highly significant in the case of isoform C (t = −4.31, p = 0.0002).

In line, a highly significant positive correlation between IL18 gene expression and HIF1α scores was observed ( r = 0.6516 and p = 0.0002; Figure 5D ).

A highly significant ( p = 0.0002) QTL, located at 38.46 cM (D19Mit53) on chromosome 19, had a LOD score of 5.78.

Similar to mid-term mortality, subgroup analysis showed that LVEF improvement was quite significant in levosimendan vs. placebo subgroups (mean difference: 5.65%, 95%CI: 2.72–8.57%, P=0.0002, I 2 =33%) ( Figure 4 ).

However, subtle recovery differences in RPS between treatments were observed at distinct recovery times after the first values taken 12 hours after the eccentric exercise: the RPS differences between 12 and 36 hours post eccentric exercise were highly significant ( p = 0.0002) with blueberries, whereas only a slight difference was observed between these two time points in the control condition ( p = 0.031).

In general, the difference in CYP2W1 expression between normal tissue and primary tumours was highly significant (P ≤ 0.0002).

Indeed there is a highly significant correlation between urinary glucose and the glucose tolerance test area under the curve (r=0.623, p=0.0002), a measure of insulin resistance not directly influenced by food intake.

The PCR product size of ECR near HMX1 (duplication of 76 bp) showed a highly significant association with ear size in Awassi sheep ( p < 0.0002), in addition to the significant difference ( p < 0.001) between affected animals (earless versus short ear) ( Table 3 ). 3.6.

There is an extremely significant Spearman’s rank correlation with k for age at peak incidence rate, both model-fitted (both: Spearman’s ρ = 0.74, P = 0.0002, n = 21; female: ρ = 0.68, P = 0.0002, n = 25; male: ρ = 0.73, P = 0.0001, n = 23) and from the SEER data (both: ρ = 0.62, P = 0.003, n = 21; female: ρ = 0.66, P = 0.0003, n = 25; male: ρ = 0.47, P = 0.02, n = 23).

Results and Discussion Metabolites and isotopic signatures With increasing CH 3 F concentration, acetate accumulated while methane accumulation was reduced accordingly ( Figure 2A ) resulting in a highly significant negative correlation (r = 0.7, P = 0.0002).