Barely Significant

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showed a trendp value < 0.0010.0× alpha
In general, the group from Portugal showed a trend of higher scores in most domains, with statistical significance in Physical Functioning ( p value < 0.001), General Health Perceptions ( p value = 0.043) and Social Role Functioning ( p value = 0.002), which impacted the total score ( p value = 0.006).
highly significantP < 0.0010.0× alphaqualifiedgold
Effect of Chrysin on the Weight Gain and Liver Index in High-Fructose-Induced NAFLD in Rats ( Figure 3 ) Rats fed with high fructose showed a highly significant weight gain compared to the normal control (86.14 ± 6.57 vs. 44 ± 6.76, P < 0.001).
near-significantp=0.0010.0× alphagold
Given the high degree of collinearity between SSmallAV and STermAV in both cohorts, and the fact that each variable demonstrated independent or near-significant associations with mortality in multivariable analyses (SSmallAV: p=0.001 in OSIC; STermAV: p∼0.05 in both cohorts) ( table 2 ), we elected to combine them into a single metric, SPAV.
highly significantP < 0.0010.0× alphaqualifiedgold
22 , 23 A comparison of median gene fold change between amyotrophic lateral sclerosis, Parkinson’s disease, primary lateral sclerosis and healthy controls using a Kruskal–Wallis analysis was highly significant for all eight miRNAs with H values ranging from 38 to 136 (critical value = 16, P < 0.001), suggesting that at least one of the disease groups was not from the same population.
highly significantP < 0.0010.0× alphaqualifiedgold
The analysis of differences in biochemical markers (TBA, AST, ALT, TBIL, and DBIL) and the clinical symptom of pruritus reached highly significant levels ( P < 0.001), strongly indicating that the severity of ICP is closely related to these biochemical changes and symptoms.
a decreasing trendP < 0.0010.0× alphagold
an increasing trendP < 0.0010.0× alphagold
Variables such as age, weight, RBC count, hemoglobin, hematocrit, albumin, PCO2, PO2, and pH showed a decreasing trend with increasing LAR ( P < 0.001), while WBC count, RDW, creatinine, BUN, ALT, AST, potassium, glucose, INR, PT, PTT, and lactate demonstrated an increasing trend with higher LAR quartiles (all P < 0.001).
highly significantp-values < 0.0010.0× alphaqualifiedgold
While the overall sample size provided sufficient statistical power for primary analyses (highly significant p-values < 0.001), gender-specific subgroup analyses (male: N = 673; female: N = 575) may have limited power to detect smaller effect sizes or subtle gender differences.