The most likely explanation for the highly significant reduction of SNV numbers at genes versus intergenic regions ( p <0.001 in case of both cisplatin and cyclophosphamide, χ 2 test) is the activity of transcription-coupled repair (TCR), which can remove single strand lesions in an error-free manner [ 40 ].
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The difference between the two conditions remained highly significant ( p < 0.001) when the data were analyzed without outlier removal. 3.
However, the effects of the two antidepressants differed, in that IMI strongly decreased the immobility time, whereas FLX produced only a marginally significant decrease (IMI: 81.5 ± 24.7 sec, p < 0.001; FLX:190.2 ± 4.29 sec, p < 0.05 vs. toluene-treated group: 207.0 ±4.33 sec, n = 6) in contrast to the effects in TST ( Fig. 3 B) .
The mean difference was − 2.87 (95% CI: -3.76 to -1.98), also highly significant ( p < 0.001).
There was a highly significant difference in MeCP2 immunoreactivity between MS15 rats and MS180 rats in the NAc core, p < 0.001, with MS15 expressing more labeled profiles than did MS180 (see Figure 5 ).
Mean maxillary arch length, arch circumference and inter-canine and inter-molar width in males as well as females was reduced as compared to the control group and this difference was statistically highly significant ( P <0.001) [ Table 4 ].
Association between perceived stress and fat intake The correlation between fat intake and perceived stress as numerical variables was significant (ρ = 0.15, p-value = 0.005), and there was evidence of an increasing trend of fat intake associated with greater perceived stress (p<0.001).
Many authors define the cutoff value of the normal ONSD as (5 mm) which supports our cutoff point gained from the control group to compare it with the corresponding values of the patients.[ 9 13 ] The current study found a highly significant statistical correlation between ONSD with direct measurement of ICP ( R = 0.933 and P < 0.001), this result goes with the latest studies done in Rome, Italy, that was performed in 2017 by Toscano et al. whose found a strong correlation between ONSD and ICP ( R = 0.895 and P < 0.001).[ 14 ] Another
Change in pain from baseline was found to be statistically highly significant ( P < 0.001) at 1 week p.o., 1 month p.o., 2 months p.o., and at 3 months p.o.
We observed both one-sided and two-sided PO to correlate with a highly significant increase of disease duration (regression coefficient 2.39 [95% CI, 1.93 to 2.83], p<0.001 and regression coefficient 4.27, [95% CI, 3.80 to 4.75], p<0.001, respectively) ( table 2B and figure 1 and online supplemental table 3B ).
The non‐linearity of Breslow thickness was highly significant ( P < 0·001) and well represented by logarithmic transformation.
Interestingly, our study also demonstrated that there was a moderately significant correlation between the expression levels of HO-1 and CD163 in TAMs with a Spearman’s correlation coefficient of 0.536 ( P < 0.001) ( Figure 2 ).
Kendall’s tau coefficient test showed highly significant correlations in scores given by the examiners (0,650–0,763, p < 0.001) to both the test and control explants.
1 and 2 ) Taking into consideration the precise localization of the recurrent plaque, 41/41(100%) specimens were unilateral (compared to 30/41 (73.2%) in pVFL; the difference is highly significant: G (1) = 17.0, p < 0.001), but in 2/41 (4.9%) patients, the lesions spread in the anterior commissure (compared to 16/25 (39.0%) in pVFL, the difference is highly significant: G (1) = 15.5, p < 0.001).
There is a significant trend to discharge patients between I and II for CAP (20% vs. 24%) and COPD (10% vs. 22%; P < 0.001).
We observed a highly significant difference in percent survival between these two genotypes (P<0.001).
Although lymphocyte counts were numerically higher in dogs with lymphoma, this difference did not reach statistical significance. In contrast, eosinophil counts were significantly lower in dogs with lymphoma compared to healthy controls ( p < 0.001).
Pearson's Chi-squared test and Fisher's exact test revealed a highly significant (p<0.001) difference between the groups and inter-rater agreement.
11 Performing a proportional hazard assumption test for our data found highly significant violation of this assumption ( P < 0.001, data have not been shown).
The difference in the detection ability was highly significant ( P <0.001; Table 4 ; Figure 10 ).
35 In addition to years of experience, prior interaction with individuals diagnosed with ASD emerged as a strong predictor of knowledge, with highly significant associations found in both bivariable and multivariable analyses (p<0.001).
Reprosil: High frequency amplitude 2 being the most prominent, produced the least mean voids (mean = 23.2000, P = 0.001, very highly significant).
MTT cell proliferation assay revealed a concentration-dependent mean optic density with G3 samples showed the highest mean (4.26 ± 0.27) followed by G2, G1 and Control G4 groups (2.55 ± 0.07, 2.37 ± 0.08 and 2.33 ± 0.17, respectively) with a highly significant difference found between all studied groups (P < 0.001).
All climate variables were highly significant ( p < .001) for the “pure" dataset, while the only significant soil variables were S_C (subsoil carbon content, p = .021), S_CEC (cation exchange capacity of the clay faction in the subsoil, p = .002), and S_GRAVEL (subsoil % gravel, p = .013).
This difference is highly significant with p < 0.001 (table 1 ).