1 Mean difference −0.62 × 10 − 3 (95% CI −1.25 to 0.01) × 10 − 3 , p = 0.06, indicating a borderline significant trend favoring darbepoetin; Fig. 2 Mean difference −0.83 × 10 − 3 (95% CI −1.46 to −0.19) × 10 − 3 , p = 0.01, demonstrating a statistically significant advantage for darbepoetin Fig. 3 Mean difference −1.45 × 10 − 3 (95% CI −2.06 to −0.83) × 10 − 3 , p < 0.00001, indicating a highly significant superiority of darbepoetin Collectively, these findings suggest that, under most study conditions, darbepoetin is likely to be more effective than short-acting epoetin in achieving or maintaining target hemoglobin concentrations.
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Moreover, our results could be conservative because the 131 threatened species in our study show a borderline significant trend towards having more missing traits than non-threatened species (Kruskal–Wallis test: p = 0.04, χ 2 = 19.96, df = 2; Supplementary Methods .
A borderline significant trend toward increased risk was observed for schizophrenia (hazard ratio [HR] = 1.82, 95% confidence interval [CI] = 1.01–3.27, P = .0410) and suicide-related outcomes (HR = 1.38, 95% CI = 0.76–2.51, P = .2858); however, these associations did not remain significant after correction for multiple comparisons ( Figure 2 ).
In this case, the cumulative incidence of discontinuation was higher in migrants across all categories, including a borderline significant trend towards higher VF (aHR 3.51, 95% CI 0.95–12.98, p = 0.045), but with substantial uncertainty given the small number of failures. 3.4 On‐Label Analysis The results of the secondary analysis, including only PWH in whom the prescription was in accordance with the technical sheet, and excluding those who had NNRTI or INSTI mutations, are presented in File S4, Tables S4.1 − S4.4 and Figure S4 . 4 Discussion In our study, migrant PWH switching to LAI CAB+RPV exhibited low VF rates, comparable to those observed in pivotal clinical trials.
For Confident , there was only a borderline significant trend ( p =0.049).
In female COPD patients, pulmonary artery (PA) diameters were higher than in controls, showing a borderline significant trend ( p = 0.050), while total lung volume negatively correlated with Vena Cava Superior (VCS) diameter ( p < 0.05).
For EPA + DHA intake, the association approached but did not reach statistical significance for all-cause mortality ( P = 0.055), while showing a borderline significant trend for cardiovascular mortality ( P = 0.050), as depicted in Fig.
Meanwhile, studies with higher proportions of patients with AFP > 400 showed a borderline significant trend toward elevated HRs for PFS ( p = 0.05).
While the weighted median method suggested a borderline significant trend ( p < 0.05), MR-Egger analysis did not confirm this association.
Finally, a non-significant trend for zinc deficiency was found in PPI users (81.2 ± 13.9 versus 87.0 ± 12.7, p = 0.08) and also a borderline significant trend for lower sodium levels in PPI users (139.8 ± 3.8 versus 141.8 ± 4.6, p = 0.05).
The sensitivity analysis, including studies where the effect size was approximated from median and interquartile range, showed a borderline significant trend towards higher image quality for DLR (summary effect size of 1.38, 95% confidence interval 0.00–2.04, p = 0.05, df = 32).
Length of hospital stay showed a borderline significant trend favoring PPF (11.00 ± 6.99 vs. 16.27 ± 13.03 days, p = 0.05).
A borderline significant trend toward increased SAE risk was observed (OR = 3.36, P = 0.05).
In contrast, heavy physical labor showed only a borderline significant trend ( P = 0.05, OR = 6.90), but its substantial effect size warranted inclusion in the model, suggesting a potential clinical relevance that merits further investigation.
Node count showed a borderline significant trend (−2.59/μm, p = 0.051), while BD was unaffected (−0.0026 mm − 2 /μm, p = 0.498).
There were no significant between group differences in total distance at any displacement, but the Avoider vs Non‐Avoider group comparison at day 5 showed a borderline significant trend ( p = 0.0526) (Figure S6C ).
Interestingly, we found a borderline significant trend ( p = 0.053) in the MRD-negative group, where patients with a higher MaxΔVAF (suggesting a larger drop from a potentially higher preoperative VAF) paradoxically showed a trend towards worse DFS (Fig. 3 A).
Aluminum foil and utensil usage were minimal, with most participants never using them, although aluminum foil showed a borderline significant trend (χ2 = 16.62, P < 0.055).
Left common carotid stenosis demonstrated a borderline significant trend ( p = 0.057), with highest prevalence in harmful drinking group (7.6%).
For persons without experience with serious mental illness personally or knowing others versus those with such experience, the total impact score for the workshop had a borderline significant trend towards more impact for those with experience (Z(1) = -1.91, p = 0.057), but no significant difference for opera total impact score (Z(1) = -1.28, p = 0.199).
Publication year showed a borderline significant trend toward lower relapse rates in more recent studies (β = −0.31, 95% CI: −0.62 to 0.01, p -value = 0.058), which could reflect improvements in patient selection or withdrawal protocols.
In the Kaplan-Meier plot comparing the groups with 1:1 matching, a borderline significant trend ( P = 0.059) can be seen, with the non-users having an earlier dementia diagnosis rate or a higher AD susceptibility than the drug user group ( Figure 4A ).
Regarding the distribution of Candida species, there was a borderline significant trend of more patients with C. tropicalis in the non-survivor group than in the survivor group (48.3% vs. 27.5%, p = 0.060).
When tested for interaction effects, there was a borderline significant trend of negative interaction observed between schizophrenia diagnosis and KL-VS Het+ on attention z -scores; β = −.56, P = .060 ( Table 2 ).
The ADR showed a borderline significant trend of decline between cataract surgeries ( P = .06), compared to baseline with significant recovery ( P = .033) after the second cataract surgery to near baseline ( Figure ).