Besides, when the stroma was denser (TSR < 1), E-cadherin expression showed a decreasing trend, exhibiting a significant statistical significance ( P = 0.002) (Supplementary Table 1).
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Furthermore, a decreasing trend in CRHp prevalence was noted for the European continent (25% in 2013–2016 to 20% (2017–2020), p = 0.002) [ 23 ].
Change in Morphine Milligram Equivalents Prior to HB21, there was a decreasing trend in MMEs per day (rate of −.09 MMEs per study month, 95% CI −.16, −.04 MMEs per study month) ( P = .002) with a mean MMEs per day of 34.7 for all opioids during the study period; following implementation there was a non-significant increase in MMEs for all opioids to 37.4 (change of 2.69 MMEs, 95% CI −.51, 5.89 MMEs) ( P = .105) ( Table 1 ; Figure 2 ).
CK Total Activity In comparison with NHBx hearts, median total CK activity was significantly lower both in SevAS-rEF (by 43%, post hoc one-sided P =0.016) and SevAS-pEF (by 35%, post hoc one-sided P =0.028), resulting in a decreasing trend in median values ( P =0.002; Figure 4 A, Table 2 ).
During the study period, isocyanate-related asthma followed a decreasing trend ( P =0.002).
Internet access significantly shifted from an increasing intraocular pressure trend to a decreasing trend in the IA group ( P =.002) among the patients who did not have any medication changes.
Tree-ring width and earlywood width exhibited a decreasing trend from pith to bark ( p = 0.002 and p < 0.001), whereas latewood width remained constant.
By day 60, ASV richness exhibited a decreasing trend with immigration in both homogenous treatments, reaching significance only in Long‐Long ( p = 0.002) but not in Fen‐Fen ( p = 0.151).
There was a decreasing trend in visual acuity with increasing severity ( P = 0.002).
Episodes portraying ARAs showed a decreasing trend over time, with more episodes featuring ARAs in the programme’s earlier years (20 episodes, 12.9%) versus the latter half (3 episodes, 2.4%, P = 0.002).
The results exhibit a decreasing trend of pH over 180 days for all samples, as indicated by the significant time effect on the pH ( P = .002) based on the GEE model with adjustment for the effect of the product on pH.
Among all age groups, the highest monoresistance was for INH (1.2%), and across age groups, only INH monoresistance showed a decreasing trend with age ( P = .002).
aeruginosa showed a >20% resistance rate for both meropenem and imipenem in most study years despite a decreasing trend in the case of meropenem ( p = 0.002) ( Supplementary Material Table S5 ). 2.6.
Figure 1 (a) shows that there were no changes in overall adherence over time ( P = 0.108) and adherence in ED-PrEP users ( P = 0.270), whereas D-PrEP users showed a decreasing trend (from 78% in the first follow-up to 73.1% after 12 months, P = 0.002).
Trend analysis of the PM 10 dataset showed a decreasing trend (Modified M–K Hamed Rao approach test result: tau ( τ ) = − 0.3, p -value = 0.002) with a low rate of 0.2 μg m −3 per annum during 2018–2020 (Fig. 5 ).
The mRNA expression of CYP27A1 and CYP27B1 were upregulated in the VDD group ( p < 0.001), VDR had a decreasing trend compared with the CON group in the brain; while the mRNA expression of CYP27A1 ( p = 0.002, p < 0.001) and CYP27B1 ( p = 0.008, p < 0.001) were downregulated, VDR ( p = 0.044, p = 0.010) was upregulated in the VDD + VD group and VDD + VD-FA/VB 12 group compared with the VDD group in the brain.
Then, in AT8, there was a decreasing trend in the ALP level after training cessation (104.1 U/L, 95% CI) at T12; the value is significantly ( p = 0.002) lower than the baseline value.
In 2007 to 2009, a decreasing trend for mean BMI was significantly observed in those with a high income ( p =0.0021).
Calcifications vary by pathological stage Both lattice parameters (‘a’ and ‘c’ axes) for HAP showed a decreasing trend with increasing pathological stage, with a significant weak negative correlation between the ‘c’ axis and pathological stage (r τ = − 0.284, p = 2.17 × 10 –3 ) (Fig. 4 a,b).
As showed in Figure 3 , all the Amsel criteria showed a decreasing trend in Active group at T1 sampling time compared to T0 (Clue cell presence p -value = 0.0023; Homogenous vaginal discharge p -value = 3.05 × 10 −5 ; Positive amine test p -value = 0.0018; Vaginal pH > 4.5 p -value = 0.049).
While BLI detected tumors at 1-week, it failed to detect tumor growth, displayed a decreasing trend overtime (slope = -9.0x10 8 ; p = 0.0028), and terminal signal did not correlate with ex vivo tumor mass (r = 0.01853; p = 0.6286).
Briefly, VTI QRS-3D showed a decreasing trend across age groups from 18 to 65 years ( p = 0.003 for females, p < 0.0001 for males).
A decreasing trend was observed for KC ( P =0.009) and an increasing trend for BK ( P =0.003) and FED ( P =0.001).
APG showed a decreasing trend until 60 min after ingestion, with a significant difference at 30 and 60 min ( p = 0.003 and p = 0.012, respectively).
Tobramycin showed a decreasing trend; however, its combination with dexamethasone increased progressively both in prescription numbers and portions ( p = 0.003 and p < 0.001).