“a decreasing trend”

Results Symptom burden exhibited a decreasing trend at each stage ( F = 36.74, p < 0.001).

A decreasing trend was also noted for the rate of penetrating keratoplasty since 2008 (P < 0.001 using MARS).

In the GCF samples of periodontitis patients, the level of miR-205-5p revealed a decreasing trend, contrary to the trend of NEAT1 ( Fig. 4 C, P < 0.001).

In general terms, BIS sensitivity showed a statistically significant effect, F (3, 803.74) = 14.82, p < 0.001, η 2 partial = 0.048, observing a decreasing trend in girls from T1 to T4, t (295) = 6.10, p < 0.001, Hedges’ g = 0.43; and boys from T2 to T4, t (295) = 2.96, p = 0.020, Hedges’ g = 0.29.

The improvement proportion revealed a decreasing trend (Cochran–Armitage Trend Test: Z = −5.277, p < 0.001) in the three subgroups of “almost naïve”, “partly naïve”, and “hardly naive”.

Hemato-oncologic diagnoses showed a decreasing trend from 8.7% in the O group to only 1.0% in the VVO group (p<0.001).

The resistance rate of cefepime decreased from 9.4% to 4.8%, showing a decreasing trend year by year ( p < 0.001).

Significant differences were observed across age groups ( χ 2 = 419.172, p < 0.001), and the detection rate showed a decreasing trend with increasing age (Cochran-Armitage trend test: Z = −20.466, p < 0.001).

Conversely, a decreasing trend was observed for deaths in health facilities ( p < 0.001).

The seasonal Mann–Kendall trend test showed a significant decreasing trend in malaria cases over the study period (z = − 6.04, p < 0.001) as well as a decreasing trend in mean temperature (z = − 12.06, p < 0.001).

While a significant decrease in EDV was not observed, there was a decreasing trend in both EDV and PSV with increasing effort (PSV: r 2 = 0.7477, p = 0.0013; EDV: r 2 = 0.3643, p = 0.0319; Figure S5 ).

The starch digestibility showed a decreasing trend with the increase in dietary amylose-amylopectin ratio ( R = −0.9893, p = 0.0013), and the values of fish fed diets 1–2 were significantly (p<0.05) higher than those of fish fed with other diets.

Treatment with GEO and citral caused a decreasing trend in plasma cholesterol and LDL-C levels in ApoE −/− mice compared with the GC group; moreover, high-dose GEO and citral increased plasma HDL-C levels ( p = 0.0015 and p = 0.0054, respectively).

PC exhibited a decreasing trend with an increase in the BMD quartile (Q1: 242.55 ± 56.12; Q2: 243.75 ± 58.61; Q3: 243.20 ± 58.40; Q4: 238.38 ± 56.79; P = 0.0017).

2 ) but remaining at the lower end of the overall copy numbers (0.05–0.2 copies/μl) and showing no significant pattern of eDNA signal accumulation over time except a decreasing trend for nylon, highly influenced by the high initial copy numbers ( p ≤ 0.0019, Fig. 3 ).

The average consumption of ciprofloxacin showed a decreasing trend (−0.4 DDD per 1000 OBD per month, p = 0.002), while the average consumption of macrolide antibiotics, betalactamase stable penicillins, and piperacillin-tazobactam showed a slightly increasing trend ( Table 2 ).

In contrast, MCDK shows a decreasing trend in Least Squares mean differences, with a significant negative difference at GA 32 ( p = 0.002), but no significant differences at 4 weeks postnatally ( p = 0.42) or at 2 years of age ( p = 0.88), suggesting that the impact diminishes over time.

By day 60, ASV richness exhibited a decreasing trend with immigration in both homogenous treatments, reaching significance only in Long‐Long ( p = 0.002) but not in Fen‐Fen ( p = 0.151).

During the study period, isocyanate-related asthma followed a decreasing trend ( P =0.002).

CK Total Activity In comparison with NHBx hearts, median total CK activity was significantly lower both in SevAS-rEF (by 43%, post hoc one-sided P =0.016) and SevAS-pEF (by 35%, post hoc one-sided P =0.028), resulting in a decreasing trend in median values ( P =0.002; Figure 4 A, Table 2 ).

Then, in AT8, there was a decreasing trend in the ALP level after training cessation (104.1 U/L, 95% CI) at T12; the value is significantly ( p = 0.002) lower than the baseline value.

Besides, when the stroma was denser (TSR < 1), E-cadherin expression showed a decreasing trend, exhibiting a significant statistical significance ( P = 0.002) (Supplementary Table 1).

The mRNA expression of CYP27A1 and CYP27B1 were upregulated in the VDD group ( p < 0.001), VDR had a decreasing trend compared with the CON group in the brain; while the mRNA expression of CYP27A1 ( p = 0.002, p < 0.001) and CYP27B1 ( p = 0.008, p < 0.001) were downregulated, VDR ( p = 0.044, p = 0.010) was upregulated in the VDD + VD group and VDD + VD-FA/VB 12 group compared with the VDD group in the brain.

Tree-ring width and earlywood width exhibited a decreasing trend from pith to bark ( p = 0.002 and p < 0.001), whereas latewood width remained constant.

Before biosimilars were introduced, originator infliximab prices presented a decreasing trend in Australia ( P = 0.002), Canada ( P < 0.001), India ( P < 0.001), Japan ( P < 0.001), and Korea ( P < 0.001).