“a pronounced trend”

pumilus SAFR-032 genome sequence from such a pronounced trend strongly indicated a high possibility of an assembly error.

As there is a pronounced trend to hip deterioration in nonambulatory children, reliable predictors for later subluxation to MP≥40% are important for follow-up policy and treatment.

In particular, families containing the largest species and those with the most pronounced morphological features indicative of algal symbionts show a pronounced trend of size decrease away from the equatorial region.

The findings revealed that the CNV identified following RT correction did not exhibit a pronounced trend of early gain and late RT loss, in comparison with those identified following GC correction or non‐correction (Figure S1D,E ).

Original results did not show a significant improvement in survival with capecitabine across all TNBC cases, but a pre-planned analysis of an IHC-defined stratum for the basal-like subtype of TNBC showed that although those expressing the basal biomarkers cytokeratin 5/6 (CK5/6) or EGFR ( 23 ) did not benefit from capecitabine, those classified as non-basal by IHC did have a highly significant benefit from capecitabine with an OS hazard ratio (HR) of 0.43 versus 1.23 ( P interaction = 0.005) and a pronounced trend toward a better DFS with an HR of 0.53 versus 0.94 ( P interaction = 0.06) for IHC non-basal versus basal ( 21 ).

A pronounced trend toward deteriorating overall survival from N‐PLN 1 to N‐PLN 2+ was observed across all tumor size categories.

As depicted in the above revolution review, electrochemical vibration sensors exhibit a pronounced trend toward structural unification and MEMS-based manufacturing methodologies.

Collectively, these findings indicate a pronounced trend of aging in HNC burden in China, Japan, and the Republic of Korea.

NBTI data demonstrated a pronounced trend—NBTI reliability is correlated with the N concentration of SiON layers, i.e., devices with a lower N content demonstrated a superior NBTI behavior (smaller Δ V t shifts and longer TTF values).

This includes a pronounced trend towards pollination-by-deceit in which orchid flowers provide a predictable suite of floral attractants but fail to offer food rewards, receptive females or suitable brood sites [ 1 , 2 ].

Notably, only the ACS of multicomponent inks exhibited a pronounced trend of initial increase followed by decrease, while the ACS of single-component inks remained relatively stable with minor changes.

For non-stationary signals such as cumulative displacement, which have a pronounced trend, the model adopts a quadratic penalty function and the alternating direction method of multipliers (ADMM) for iterative optimisation and sets a convergence tolerance to guarantee decomposition accuracy.

kousa did not exhibit a marked decline under future climate scenarios, its genetic structure displayed a pronounced trend toward homogenization.

However, a pronounced trend of hypomethylation (Δ methylation > 0.1) in PMDs and a minor shift toward hypomethylation (Δ methylation ≤ 0.1) was found in HMDs for S2 iCCAs, respectively (Supplementary Fig.

There was a change in the intensity indicator, which is calculated per 100 thousand of the population of the republic, a pronounced trend towards a decrease in figures with an annual rate of decrease of 3.4% registered upon monitoring various anatomical areas.

Furthermore, the analysis of D7SPSE-connected genes using D0 and D7 RNA-seq data indicates a pronounced trend for genes under D7SPSE regulation to be preferentially expressed in surface ectoderm cells (D7) as opposed to hESCs (D0), as illustrated in Fig. 2D .

But at the same time, it has been shown that patients with pathogenic mutations in the tumor, at the level of a pronounced trend, have shorter overall survival compared with the group of patients in whom mutations with unidentified clinical significance were found (11.1 versus 17.9 months, log-rank test p = 0.07) [ 50 ].

Clockwise pressure–temperature evolutionary paths within the Western Granulites show a pronounced trend of isothermal decompression (ITD), which differs from IBC reported for the Eastern Granulites ( Fig. 7 ).

A significant majority of patients undergo cochlear implant, indicating a pronounced trend toward surgical intervention within this population.

The differences in the antibody titers induced through the different DNA- and protein-based vaccines did not reach statistical significance, although recombinant proteins showed a pronounced trend to induce higher antibody titers than vector DNAs at the dosages used here ( Figure 3A ).

These findings indicated that there is a pronounced trend toward Khib upregulation in the AD brain.

2 d, there is a pronounced trend where classes with higher average confidence tend to have higher accuracy.

A 2025 report by the Organization for Economic Cooperation and Development (OECD) indicates that healthcare expenditure as a percentage of GDP shows a pronounced trend of rigid growth in most countries.

However, a pronounced trend over increasing concentrations was not observed (Figure 8 B, hexagons and crosses and Table 2 ).

Overall, research on microglia in SCI demonstrates a pronounced trend of rapid development. 3.2.